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A component of NF-kappa B transcription factor. It is proteolytically processed from NF-kappa B p100 precursor protein and is important for maturation of B-LYMPHOCYTES and adaptive HUMORAL IMMUNITY.
Entry Term(s)
NF-kappa B p100 Precursor Protein
NF-kappaB p52
NF-kappaB p52 Subunit
NF-kappaB2
NF-kappaB2 p100
NFKB2 Transcription Factor
NK-kappa B p52
Transcription Factor H2TF1
Registry Numbers
0
Public MeSH Note
2006; NF-KAPPAB P52 SUBUNIT was indexed under NF-KAPPA B 1994-2005, & under TRANSCRIPTION FACTORS 1993
A component of NF-kappa B transcription factor. It is proteolytically processed from NF-kappa B p100 precursor protein and is important for maturation of B-LYMPHOCYTES and adaptive HUMORAL IMMUNITY.
NF-kappa B p100 precursor protein helps retain TRANSCRIPTION FACTOR RELB in the CYTOPLASM and its full-length form inhibits NF-kappa B signaling. It is processed by the PROTEASOME to produce NF-kappa B p52 subunit.