MeSH Browser

MeSH Heading: DNA Polymerase theta
Tree Number(s): D08.811.913.696.445.308.300.622
Unique ID: D000097462
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000097462
Scope Note: A specialized DNA polymerase that in humans is encoded by the POLQ gene. It is involved in DNA repair pathways, including DNA END-JOINING REPAIR and RECOMBINATIONAL DNA REPAIR.
Entry Term(s): DNA Polymerase POLQ
Registry Numbers: EC 2.7.7.-
Public MeSH Note: 2024; DNA POLYMERASE THETA was indexed under DNA-DIRECTED DNA POLYMERASE 1999-2023
History Note: 2024 (1999)
Date Established: 2024/01/01
Date of Entry: 2023/07/26
Revision Date: 2023/05/30

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

DNA Polymerase theta MeSH Descriptor Data 2025