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Gene Products, nef MeSH Descriptor Data 2025


MeSH Heading
Gene Products, nef
Tree Number(s)
D12.776.964.775.362
D12.776.964.925.500
Unique ID
D015693
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D015693
Scope Note
Products of the retroviral NEF GENE. They play a role as accessory proteins that influence the rate of viral infectivity and the destruction of the host immune system. nef gene products were originally found as factors that trans-suppress viral replication and function as negative regulators of transcription. nef stands for negative factor.
Entry Term(s)
3'-orf Protein
Gene Product, nef
nef Gene Products
nef Protein
Previous Indexing
Retroviridae Proteins (1987-1989)
Viral Proteins (1987-1988)
Public MeSH Note
91; was see under VIRAL REGULATORY PROTEINS 1990
History Note
91(90); was see under VIRAL REGULATORY PROTEINS 1990
Date Established
1991/01/01
Date of Entry
1989/10/20
Revision Date
2007/07/09
Gene Products, nef Preferred
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