MeSH Browser

MeSH Heading: Pseudomonas aeruginosa Exotoxin A
Tree Number(s): D08.811.913.400.725.115.826; D23.946.123.574; D23.946.350.625; D23.946.896.245
Unique ID: D000097668
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000097668
Scope Note: An NAD-dependent ADP-ribosyltransferase that catalyzes the transfer of the ADP ribosyl moiety of oxidized NAD onto elongation factor 2 (EF-2) thus arresting protein synthesis. Commonly used as the toxin in immunotoxins.
Entry Term(s): ETA, Pseudomonas; Exotoxin A, Pseudomonas; Exotoxin A, Pseudomonas aeruginosa; PE38QQR; PE40 toxin; Recombinant Truncated Pseudomonas Exotoxin A, Form PE38QQR; Recombinant Truncated Pseudomonas Exotoxin A, Form PE40; ToxA protein, Pseudomonas aeruginosa
Public MeSH Note: PSEUDOMONAS AERUGINOSA EXOTOXIN A was indexed under BACTERIAL TOXINS, EXOTOXINS, ADP RIBOSE TRANSFERASES and VIRULENCE FACTORS 2022-2023
History Note: 2024 (2022)
Date Established: 2024/01/01
Date of Entry: 2023/07/26
Revision Date: 2023/06/12

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000758363
Scope Note: An NAD-dependent ADP-ribosyltransferase that catalyzes the transfer of the ADP ribosyl moiety of oxidized NAD onto elongation factor 2 (EF-2) thus arresting protein synthesis. Commonly used as the toxin in immunotoxins.
Terms: Pseudomonas aeruginosa Exotoxin A Preferred Term
Term UI T001137054
Date04/27/2023
LexicalTag NON
ThesaurusID NLM (2024); ETA, Pseudomonas
Term UI T001124022
Date08/29/2022
LexicalTag NON
ThesaurusID NLM (2022); Exotoxin A, Pseudomonas aeruginosa
Term UI T001137056
Date04/27/2023
LexicalTag NON
ThesaurusID NLM (2024); ToxA protein, Pseudomonas aeruginosa
Term UI T001137057
Date04/27/2023
LexicalTag NON
ThesaurusID NLM (2024); Exotoxin A, Pseudomonas
Term UI T001137055
Date04/27/2023
LexicalTag NON
ThesaurusID NLM (2024)

Pseudomonas aeruginosa Exotoxin A MeSH Descriptor Data 2025