MeSH Browser

MeSH Heading: NAD+ Nucleosidase
Tree Number(s): D08.811.277.450.430.400; D08.811.913.400.725.115.660
Unique ID: D009244
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D009244
Scope Note: An enzyme that catalyzes the hydrolysis of nicotinamide adenine dinucleotide (NAD) to NICOTINAMIDE and ADENOSINE DIPHOSPHATE RIBOSE. Some are extracellular (ectoenzymes).The enzyme from some sources also catalyses the hydrolysis of nicotinamide adenine dinucleotide phosphate (NADP).
Entry Term(s): DPNase; Diphosphopyridine Nucleotidase; Diphosphopyridine Nucleotidases; Ecto-NAD+ Glycohydrolase; NAD(P) Nucleosidase; NAD+ Glycohydrolase; NAD+ Nucleosidases; NAD-Glycohydrolase; NAD-Glycohydrolases; NADP Nucleosidase; NADP-Glycohydrolase; NADase; NADases
Registry Number: EC 3.2.2.5
Related Numbers: 9032-65-9; EC 3.2.2.6
CAS Type 1 Name: NAD+ glycohydrolase
Previous Indexing: NAD (1973-1974); Nucleosidases (1973-1974)
Public MeSH Note: 1994; see NAD NUCLEOSIDASE 1975-1993; NAD(P) NUCLEOSIDASE was indexed under N-GLYCOSYL HYDROLASES 1982-2002, NAD 1973-1981
History Note: 1994 (1975); use NAD NUCLEOSIDASE 1977-1993; for NAD(P) NUCLEOSIDASE use NAD+ NUCLEOSIDASE (NM) 1973-2002
Date Established: 1977/01/01
Date of Entry: 1974/11/19
Revision Date: 2006/07/05

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Glycoside Hydrolases [D08.811.277.450]
      - N-Glycosyl Hydrolases [D08.811.277.450.430]
        
        DNA Glycosylases [D08.811.277.450.430.099]
        
        NAD+ Nucleosidase [D08.811.277.450.430.400]
        
        ADP-ribosyl Cyclase [D08.811.277.450.430.400.060]
        
        Ribosome Inactivating Proteins [D08.811.277.450.430.700]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Transferases [D08.811.913]
    - Glycosyltransferases [D08.811.913.400]
      - Pentosyltransferases [D08.811.913.400.725]
        
        ADP Ribose Transferases [D08.811.913.400.725.115]
        
        Cholera Toxin [D08.811.913.400.725.115.180]
        
        Diphtheria Toxin [D08.811.913.400.725.115.220]
        
        NAD+ Nucleosidase [D08.811.913.400.725.115.660]
        
        ADP-ribosyl Cyclase [D08.811.913.400.725.115.660.060]
        
        Pertussis Toxin [D08.811.913.400.725.115.680]
        
        Poly(ADP-ribose) Polymerases [D08.811.913.400.725.115.690]
        
        Sirtuins [D08.811.913.400.725.115.961]

NAD+ Nucleosidase Preferred

Concept UI: M0014405
Registry Number: EC 3.2.2.5
Related Numbers: 9032-65-9; EC 3.2.2.6
Scope Note: An enzyme that catalyzes the hydrolysis of nicotinamide adenine dinucleotide (NAD) to NICOTINAMIDE and ADENOSINE DIPHOSPHATE RIBOSE. Some are extracellular (ectoenzymes).The enzyme from some sources also catalyses the hydrolysis of nicotinamide adenine dinucleotide phosphate (NADP).
Terms: NAD+ Nucleosidase Preferred Term
Term UI T027571
Date01/01/1999
LexicalTag ACX
ThesaurusID NLM (1975); NAD+ Glycohydrolase
Term UI T027572
Date08/21/1980
LexicalTag NON
ThesaurusID UNK (19XX); NAD-Glycohydrolase
Term UI T027573
Date09/18/1981
LexicalTag NON
ThesaurusID UNK (19XX); NAD-Glycohydrolases
Term UI T481798
Date02/13/2002
LexicalTag ACX
ThesaurusID NLM (2003); Diphosphopyridine Nucleotidase
Term UI T475629
Date01/02/2002
LexicalTag NON
ThesaurusID NLM (2003); NAD+ Nucleosidases
Term UI T481795
Date02/13/2002
LexicalTag ACX
ThesaurusID NLM (2003); Diphosphopyridine Nucleotidases
Term UI T481796
Date02/13/2002
LexicalTag NON
ThesaurusID NLM (2003); NADases
Term UI T481797
Date02/13/2002
LexicalTag ACX
ThesaurusID NLM (2003); DPNase
Term UI T027570
Date11/11/1974
LexicalTag NON
ThesaurusID UNK (19XX); NADase
Term UI T027574
Date11/11/1974
LexicalTag NON
ThesaurusID UNK (19XX)

NAD(P) Nucleosidase Related

Ecto-NAD+ Glycohydrolase Narrower

NAD+ Nucleosidase MeSH Descriptor Data 2023