Because of a lapse in government funding, the information on this
website may not be up to date, transactions submitted via the
website may not be processed, and the agency may not be able to
respond to inquiries until appropriations are enacted. The NIH
Clinical Center (the research hospital of NIH) is open. For more
details about its operating status, please visit
cc.nih.gov. Updates
regarding government operating status and resumption of normal
operations can be found at
opm.gov.
A family of DNA repair enzymes that recognize damaged nucleotide bases and remove them by hydrolyzing the N-glycosidic bond that attaches them to the sugar backbone of the DNA molecule. The process called BASE EXCISION REPAIR can be completed by a DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE which excises the remaining RIBOSE sugar from the DNA.
Entry Term(s)
DNA Glycosylase
DNA N-glycosidase
Methylpurine DNA Glycosylase
Registry Numbers
EC 3.2.2.-
EC 3.2.2.-
Previous Indexing
DNA (1978-1981)
Glycoside Hydrolases (1978-1981)
N-Glycosyl Hydrolases (1982-2003)
Public MeSH Note
2004; DNA GLYCOSIDASES was indexed under N-GLYCOSIDE HYDROLASES 1982-2003, under GLYCOSIDE HYDROLASES & DNA 1978-1981
A family of DNA repair enzymes that recognize damaged nucleotide bases and remove them by hydrolyzing the N-glycosidic bond that attaches them to the sugar backbone of the DNA molecule. The process called BASE EXCISION REPAIR can be completed by a DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE which excises the remaining RIBOSE sugar from the DNA.