MeSH Browser

MeSH Heading: Thymine DNA Glycosylase
Tree Number(s): D08.811.074.249.750; D08.811.277.450.430.099.750
Unique ID: D044502
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D044502
Scope Note: An enzyme that removes THYMINE and URACIL bases mispaired with GUANINE through hydrolysis of their N-glycosidic bond. These mispaired nucleotides generally occur through the hydrolytic DEAMINATION of 5-METHYLCYTOSINE to thymine.
Entry Term(s): G-T Mismatch-Specific Thymine DNA Glycosylase; Thymine Glycol DNA Glycosylase; Thymine Glycol Glycosylase
Registry Number: EC 3.2.2.-
Previous Indexing: Endodeoxyribonucleases (1991-2003)
Public MeSH Note: 2004; THYMIDINE DNA GLYCOSYLASE was indexed under ENDODEOXYRIBONUCLEASES 1991-2003
History Note: 2004; use THYMINE DNA GLYCOSYLASE (NM) 1991-2003
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2006/07/05

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0073437
Registry Number: EC 3.2.2.-
Scope Note: An enzyme that removes THYMINE and URACIL bases mispaired with GUANINE through hydrolysis of their N-glycosidic bond. These mispaired nucleotides generally occur through the hydrolytic DEAMINATION of 5-METHYLCYTOSINE to thymine.
Terms: Thymine DNA Glycosylase Preferred Term
Term UI T103440
LexicalTag ABX
ThesaurusID NLM (2004); Thymine Glycol Glycosylase
Term UI T103442
LexicalTag NON
ThesaurusID NLM (2004); G-T Mismatch-Specific Thymine DNA Glycosylase
Term UI T531589
Date01/31/2003
LexicalTag ABX
ThesaurusID NLM (2004); Thymine Glycol DNA Glycosylase
Term UI T103441
LexicalTag ABX
ThesaurusID NLM (2004)

Thymine DNA Glycosylase MeSH Descriptor Data 2023