MeSH Browser

MeSH Heading: Ribosome Inactivating Proteins
Tree Number(s): D08.811.277.450.430.700; D12.776.765.710
Unique ID: D054788
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D054788
Scope Note: N-Glycosidases that remove adenines from RIBOSOMAL RNA, depurinating the conserved alpha-sarcin loop of 28S RIBOSOMAL RNA. They often consist of a toxic A subunit and a binding lectin B subunit. They may be considered as PROTEIN SYNTHESIS INHIBITORS. They are found in many PLANTS and have cytotoxic and antiviral activity.
Entry Term(s): Polynucleotide Adenosine Glycosidase; RIP (Ribosome Inactivating Proteins); RIP Ribosome Inactivating Proteins; RNA Glycosylase; RNA N-Glycosidase; rRNA N-Glycosylases
Pharm Action: Protein Synthesis Inhibitors
Previous Indexing: N-Glycosyl Hydrolases (1988-2007)
Public MeSH Note: 2008; RNA N-GLYCOSIDASE was indexed under N-GLYCOSYL HYDROLASES 1988-2007
History Note: 2008(1988)
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 2021/06/30

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0154457
Scope Note: N-Glycosidases that remove adenines from RIBOSOMAL RNA, depurinating the conserved alpha-sarcin loop of 28S RIBOSOMAL RNA. They often consist of a toxic A subunit and a binding lectin B subunit. They may be considered as PROTEIN SYNTHESIS INHIBITORS. They are found in many PLANTS and have cytotoxic and antiviral activity.
Terms: Ribosome Inactivating Proteins Preferred Term
Term UI T693595
Date03/14/2007
LexicalTag NON
ThesaurusID NLM (2008); Polynucleotide Adenosine Glycosidase
Term UI T184461
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2008); RIP (Ribosome Inactivating Proteins)
Term UI T696784
Date05/04/2007
LexicalTag NON
ThesaurusID NLM (2008); RNA Glycosylase
Term UI T184460
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2008); RNA N-Glycosidase
Term UI T184462
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2008); rRNA N-Glycosylases
Term UI T696785
Date05/04/2007
LexicalTag NON
ThesaurusID NLM (2008); RIP Ribosome Inactivating Proteins
Term UI T001105245
Date04/26/2021
LexicalTag NON
ThesaurusID NLM (2022)

Ribosome Inactivating Proteins MeSH Descriptor Data 2025