MeSH Browser

MeSH Heading: Protein Synthesis Inhibitors
Tree Number(s): D27.505.519.389.760
Unique ID: D011500
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D011500
Scope Note: Compounds which inhibit the synthesis of proteins. They are usually ANTI-BACTERIAL AGENTS or toxins. Mechanism of the action of inhibition includes the interruption of peptide-chain elongation, the blocking the A site of ribosomes, the misreading of the genetic code or the prevention of the attachment of oligosaccharide side chains to glycoproteins.
Entry Version: PROTEIN SYN INHIB
Entry Term(s): Protein Synthesis Antagonist; Protein Synthesis Antagonists; Protein Synthesis Inhibitor
Previous Indexing: Proteins/biosynthesis (1966-1987)
Public MeSH Note: 88
History Note: 88
Date Established: 1988/01/01
Date of Entry: 1987/04/09
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0017875
Scope Note: Compounds which inhibit the synthesis of proteins. They are usually ANTI-BACTERIAL AGENTS or toxins. Mechanism of the action of inhibition includes the interruption of peptide-chain elongation, the blocking the A site of ribosomes, the misreading of the genetic code or the prevention of the attachment of oligosaccharide side chains to glycoproteins.
Terms: Protein Synthesis Inhibitors Preferred Term
Term UI T033979
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1988); Protein Synthesis Inhibitor
Term UI T000998400
Date11/20/2019
LexicalTag NON
ThesaurusID NLM (2021); Protein Synthesis Antagonist
Term UI T000998401
Date11/20/2019
LexicalTag NON
ThesaurusID NLM (2021); Protein Synthesis Antagonists
Term UI T033978
Date04/09/1987
LexicalTag NON
ThesaurusID UNK (19XX)

Protein Synthesis Inhibitors MeSH Descriptor Data 2025