MeSH Browser

MeSH Heading: Cyclooxygenase Inhibitors
Tree Number(s): D27.505.519.389.310; D27.505.696.663.850.014.040.500.500; D27.505.954.158.030.500; D27.505.954.329.030.500
Unique ID: D016861
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D016861
Scope Note: Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes.
Entry Version: CYCLOOXYGENASE INHIB
Entry Term(s): Cyclo-Oxygenase Inhibitor; Cyclo-Oxygenase Inhibitors; Cyclooxygenase Inhibitor; Inhibitors, Cyclo-Oxygenase; Inhibitors, Cyclooxygenase; Inhibitors, Prostaglandin Synthase; Inhibitors, Prostaglandin-Endoperoxide Synthase; Prostaglandin Endoperoxide Synthase Inhibitor; Prostaglandin Endoperoxide Synthase Inhibitors; Prostaglandin Synthase Inhibitor; Prostaglandin Synthase Inhibitors; Prostaglandin Synthesis Antagonist; Prostaglandin Synthesis Antagonists
Previous Indexing: Prostaglandin-Endoperoxide Synthase/antagonists & inhibitors (1981-1991)
Public MeSH Note: 92; PROSTAGLANDIN SYNTHESIS ANTAGONISTS was see ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL 1987-94
Online Note: use ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL to search PROSTAGLANDIN SYNTHESIS ANTAGONISTS 1987-94
History Note: 92; PROSTAGLANDIN SYNTHESIS ANTAGONISTS was see ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL 1987-94
Date Established: 1992/01/01
Date of Entry: 1991/07/18
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Chemical Actions and Uses [D27]
- Pharmacologic Actions [D27.505]
  - Molecular Mechanisms of Pharmacological Action [D27.505.519]
    - Enzyme Inhibitors [D27.505.519.389]

Chemical Actions and Uses [D27]
- Pharmacologic Actions [D27.505]
  - Physiological Effects of Drugs [D27.505.696]
    - Peripheral Nervous System Agents [D27.505.696.663]
      - Sensory System Agents [D27.505.696.663.850]
        
        Analgesics [D27.505.696.663.850.014]
        
        Analgesics, Non-Narcotic [D27.505.696.663.850.014.040]
        
        Anti-Inflammatory Agents, Non-Steroidal [D27.505.696.663.850.014.040.500]
        
        Cyclooxygenase Inhibitors [D27.505.696.663.850.014.040.500.500]
        
        Cyclooxygenase 2 Inhibitors [D27.505.696.663.850.014.040.500.500.500]

Chemical Actions and Uses [D27]
- Pharmacologic Actions [D27.505]
  - Therapeutic Uses [D27.505.954]
    - Anti-Inflammatory Agents [D27.505.954.158]
      - Anti-Inflammatory Agents, Non-Steroidal [D27.505.954.158.030]
        
        Cyclooxygenase Inhibitors [D27.505.954.158.030.500]
        
        Cyclooxygenase 2 Inhibitors [D27.505.954.158.030.500.500]

Chemical Actions and Uses [D27]
- Pharmacologic Actions [D27.505]
  - Therapeutic Uses [D27.505.954]
    - Antirheumatic Agents [D27.505.954.329]
      - Anti-Inflammatory Agents, Non-Steroidal [D27.505.954.329.030]
        
        Cyclooxygenase Inhibitors [D27.505.954.329.030.500]
        
        Cyclooxygenase 2 Inhibitors [D27.505.954.329.030.500.500]

Cyclooxygenase Inhibitors Preferred

Cyclooxygenase Inhibitors MeSH Descriptor Data 2025