MeSH Browser

MeSH Heading: Anti-Inflammatory Agents, Non-Steroidal
Tree Number(s): D27.505.696.663.850.014.040.500; D27.505.954.158.030; D27.505.954.329.030
Unique ID: D000894
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000894
Scope Note: Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
Entry Version: NSAID
Entry Term(s): Analgesics, Anti-Inflammatory; Anti Inflammatory Agents, Nonsteroidal; Antiinflammatory Agents, Non Steroidal; Antiinflammatory Agents, Nonsteroidal; Aspirin-Like Agent; Aspirin-Like Agents; NSAID; NSAIDs; Non-Steroidal Anti-Inflammatory Agent; Non-Steroidal Anti-Inflammatory Agents; Nonsteroidal Anti-Inflammatory Agent; Nonsteroidal Anti-Inflammatory Agents
NLM Classification #: QV 95
Previous Indexing: Analgesics, Anti-Inflammatory (1966-1986); Anti-Inflammatory Agents (1966-1986)
Public MeSH Note: 87; ANALGESICS, ANTI-INFLAMMATORY was heading 1975-89
Online Note: use ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL to search ANALGESICS, ANTI-INFLAMMATORY 1975-89
History Note: 87; ANALGESICS, ANTI-INFLAMMATORY was heading 1975-89
Date Established: 1987/01/01
Date of Entry: 1986/06/23
Revision Date: 2021/06/30

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Chemical Actions and Uses [D27]
- Pharmacologic Actions [D27.505]
  - Physiological Effects of Drugs [D27.505.696]
    - Peripheral Nervous System Agents [D27.505.696.663]
      - Sensory System Agents [D27.505.696.663.850]
        
        Analgesics [D27.505.696.663.850.014]
        
        Analgesics, Non-Narcotic [D27.505.696.663.850.014.040]
        
        Anti-Inflammatory Agents, Non-Steroidal [D27.505.696.663.850.014.040.500]
        
        Cyclooxygenase Inhibitors [D27.505.696.663.850.014.040.500.500]

Chemical Actions and Uses [D27]
- Pharmacologic Actions [D27.505]
  - Therapeutic Uses [D27.505.954]
    - Anti-Inflammatory Agents [D27.505.954.158]

Chemical Actions and Uses [D27]
- Pharmacologic Actions [D27.505]
  - Therapeutic Uses [D27.505.954]
    - Antirheumatic Agents [D27.505.954.329]
      - Anti-Inflammatory Agents, Non-Steroidal [D27.505.954.329.030]
        
        Cyclooxygenase Inhibitors [D27.505.954.329.030.500]
      - Gout Suppressants [D27.505.954.329.337]

Anti-Inflammatory Agents, Non-Steroidal Preferred

Concept UI: M0001335
Scope Note: Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
Terms: Anti-Inflammatory Agents, Non-Steroidal Preferred Term
Term UI T002617
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1987); Non-Steroidal Anti-Inflammatory Agent
Term UI T000998941
Date11/21/2019
LexicalTag NON
ThesaurusID NLM (2021); NSAID
Term UI T000998942
Date11/21/2019
LexicalTag NON
ThesaurusID NLM (2021); Nonsteroidal Anti-Inflammatory Agent
Term UI T000998943
Date11/21/2019
LexicalTag NON
ThesaurusID NLM (2021); Anti Inflammatory Agents, Nonsteroidal
Term UI T002618
Date07/11/1986
LexicalTag NON
ThesaurusID UNK (19XX); Antiinflammatory Agents, Non Steroidal
Term UI T002620
Date06/25/1986
LexicalTag NON
ThesaurusID UNK (19XX); Antiinflammatory Agents, Nonsteroidal
Term UI T002621
Date03/29/1990
LexicalTag NON
ThesaurusID NLM (1991); Non-Steroidal Anti-Inflammatory Agents
Term UI T002616
Date06/23/1986
LexicalTag NON
ThesaurusID UNK (19XX); Nonsteroidal Anti-Inflammatory Agents
Term UI T002619
Date03/29/1990
LexicalTag NON
ThesaurusID NLM (1991); NSAIDs
Term UI T002622
Date01/31/1994
LexicalTag ABB
ThesaurusID NLM (1995)

Analgesics, Anti-Inflammatory Narrower

Aspirin-Like Agents Narrower

Anti-Inflammatory Agents, Non-Steroidal MeSH Descriptor Data 2025