Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

NLM Logo

DNA Ligases MeSH Descriptor Data 2026


MeSH Heading
DNA Ligases
Tree Number(s)
D08.811.074.500
D08.811.464.754.600
Unique ID
D011088
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D011088
Annotation
do not confuse entry term POLYDEOXYRIBONUCLEOTIDE SYNTHETASES with entry term POLYRIBONUCLEOTIDE SYNTHETASE
Scope Note
Poly(deoxyribonucleotide):poly(deoxyribonucleotide)ligases. Enzymes that catalyze the joining of preformed deoxyribonucleotides in phosphodiester linkage during genetic processes during repair of a single-stranded break in duplex DNA. The class includes both EC 6.5.1.1 (ATP) and EC 6.5.1.2 (NAD).
Entry Term(s)
DNA Joinases
DNA Ligase
Polydeoxyribonucleotide Ligases
Polydeoxyribonucleotide Synthetases
T4 DNA Ligase
Registry Numbers
EC 6.5.1.-
0
Previous Indexing
Polynucleotide Synthetases (1974-1977)
Public MeSH Note
98; see POLYDEOXYRIBONUCLEOTIDE SYNTHETASES 1991-97, see POLYNUCLEOTIDE SYNTHETASES 1978-90; for DNA LIGASES see POLYNUCLEOTIDE SYNTHETASES 1974-77, & see DNA LIGASE 1973-76
History Note
98(77); for DNA LIGASES use POLYNUCLEOTIDE SYNTHETASES 1973-76
Date Introduced
1991/01/01
Last Updated
2020/05/27
DNA Ligases Preferred
T4 DNA Ligase Narrower
page delivered in 0.126s