Micrococcal Nuclease MeSH Descriptor Data 2025

MeSH Heading: Micrococcal Nuclease
Tree Number(s): D08.811.277.352.335.350.500; D08.811.277.352.355.325.500; D08.811.277.352.355.350.500; D08.811.277.352.700.350.500
Unique ID: D008836
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D008836
Scope Note: An enzyme that catalyzes the endonucleolytic cleavage to 3'-phosphomononucleotide and 3'-phospholigonucleotide end-products. It can cause hydrolysis of double- or single-stranded DNA or RNA. (From Enzyme Nomenclature, 1992) EC 3.1.31.1.
Entry Term(s): Staphylococcal Nuclease; TNase; Thermonuclease; Thermostable Nuclease
Public MeSH Note: 73
History Note: 73(65)
Date Established: 1973/01/01
Date of Entry: 1999/01/01
Revision Date: 2003/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Esterases [D08.811.277.352]
      - Deoxyribonucleases [D08.811.277.352.335]
        
        Endodeoxyribonucleases [D08.811.277.352.335.350]
        
        Deoxyribonuclease (Pyrimidine Dimer) [D08.811.277.352.335.350.137]
        
        Deoxyribonuclease I [D08.811.277.352.335.350.250]
        
        Deoxyribonuclease IV (Phage T4-Induced) [D08.811.277.352.335.350.275]
        
        DNA Restriction Enzymes [D08.811.277.352.335.350.300]
        
        Holliday Junction Resolvases [D08.811.277.352.335.350.400]
        
        Micrococcal Nuclease [D08.811.277.352.335.350.500]
        
        Mismatch Repair Endonuclease PMS2 [D08.811.277.352.335.350.600]
        
        MRE11 Homologue Protein [D08.811.277.352.335.350.650]
        
        Single-Strand Specific DNA and RNA Endonucleases [D08.811.277.352.335.350.700]
        
        Transcription Activator-Like Effector Nucleases [D08.811.277.352.335.350.850]
        
        Zinc Finger Nucleases [D08.811.277.352.335.350.925]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Esterases [D08.811.277.352]
      - Endonucleases [D08.811.277.352.355]
        
        Endodeoxyribonucleases [D08.811.277.352.355.325]
        
        CRISPR-Associated Protein 9 [D08.811.277.352.355.325.150]
        
        DNA Restriction Enzymes [D08.811.277.352.355.325.300]
        
        Flap Endonucleases [D08.811.277.352.355.325.350]
        
        Holliday Junction Resolvases [D08.811.277.352.355.325.400]
        
        Micrococcal Nuclease [D08.811.277.352.355.325.500]
        
        MRE11 Homologue Protein [D08.811.277.352.355.325.600]
        
        Single-Strand Specific DNA and RNA Endonucleases [D08.811.277.352.355.325.700]
        
        Zinc Finger Nucleases [D08.811.277.352.355.325.850]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Esterases [D08.811.277.352]
      - Endonucleases [D08.811.277.352.355]
        
        Endoribonucleases [D08.811.277.352.355.350]
        
        Micrococcal Nuclease [D08.811.277.352.355.350.500]
        
        Ribonuclease H [D08.811.277.352.355.350.700]
        
        Ribonuclease, Pancreatic [D08.811.277.352.355.350.715]
        
        Ribonuclease T1 [D08.811.277.352.355.350.725]
        
        RNA-Induced Silencing Complex [D08.811.277.352.355.350.810]
        
        Single-Strand Specific DNA and RNA Endonucleases [D08.811.277.352.355.350.820]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Esterases [D08.811.277.352]
      - Ribonucleases [D08.811.277.352.700]
        
        Endoribonucleases [D08.811.277.352.700.350]
        
        Eosinophil Cationic Protein [D08.811.277.352.700.350.262]
        
        Eosinophil-Derived Neurotoxin [D08.811.277.352.700.350.381]
        
        Micrococcal Nuclease [D08.811.277.352.700.350.500]
        
        Ribonuclease H [D08.811.277.352.700.350.700]
        
        Ribonuclease III [D08.811.277.352.700.350.707]
        
        Ribonuclease P [D08.811.277.352.700.350.711]
        
        Ribonuclease, Pancreatic [D08.811.277.352.700.350.715]
        
        Ribonuclease T1 [D08.811.277.352.700.350.725]
        
        RNA-Induced Silencing Complex [D08.811.277.352.700.350.810]
        
        Single-Strand Specific DNA and RNA Endonucleases [D08.811.277.352.700.350.850]

Micrococcal Nuclease Preferred

Concept UI: M0013774
Scope Note: An enzyme that catalyzes the endonucleolytic cleavage to 3'-phosphomononucleotide and 3'-phospholigonucleotide end-products. It can cause hydrolysis of double- or single-stranded DNA or RNA. (From Enzyme Nomenclature, 1992) EC 3.1.31.1.
Terms: Micrococcal Nuclease Preferred Term
Term UI T026437
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1965); Staphylococcal Nuclease
Term UI T026438
Date10/18/1974
LexicalTag NON
ThesaurusID UNK (19XX); Thermonuclease
Term UI T026439
Date08/04/1980
LexicalTag NON
ThesaurusID UNK (19XX); Thermostable Nuclease
Term UI T026440
Date06/09/1989
LexicalTag NON
ThesaurusID NLM (1990); TNase
Term UI T026441
Date08/18/1980
LexicalTag NON
ThesaurusID UNK (19XX)

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