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Alefacept MeSH Descriptor Data 2025


MeSH Heading
Alefacept
Tree Number(s)
D09.400.430.890.034.500
D12.776.124.486.485.114.619.393.131
D12.776.124.790.651.114.619.393.131
D12.776.377.715.548.114.619.393.131
D12.776.395.550.034.500
D12.776.543.550.158.500
D12.776.828.300.100
Unique ID
D000077944
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000077944
Scope Note
A recombinant human fusion protein of LFA-3 antigen and immunoglobulin IGG1 that binds to CD2 ANTIGENS on memory T-LYMPHOCYTES, preventing their activation and proliferation. It is used in the management of moderate to severe chronic plaque PSORIASIS.
Entry Term(s)
Amevive
LFA-3 IgG(1) Fusion Protein
LFA-3 IgG1 Fusion Protein
Pharm Action
Dermatologic Agents
Immunologic Factors
Related Numbers
222535-22-0
Public MeSH Note
2019; ALEFACEPT was indexed under RECOMBINANT FUSION PROTEINS 2000-2018
History Note
2019 (2000)
Date Established
2019/01/01
Date of Entry
2018/07/09
Revision Date
2023/03/16
Alefacept Preferred
Amevive Narrower
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