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Paraproteins MeSH Descriptor Data 2025


MeSH Heading
Paraproteins
Tree Number(s)
D12.776.124.486.485.900
D12.776.124.790.651.900
D12.776.377.715.548.900
Unique ID
D010266
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D010266
Scope Note
Abnormal immunoglobulins synthesized by atypical cells of the MONONUCLEAR PHAGOCYTE SYSTEM. Paraproteins containing only light chains lead to Bence Jones paraproteinemia, while the presence of only atypical heavy chains leads to heavy chain disease. Most of the paraproteins show themselves as an M-component (monoclonal gammopathy) in electrophoresis. Diclonal and polyclonal paraproteins are much less frequently encountered.
Entry Term(s)
Paraprotein
Pharm Action
Immunologic Factors
NLM Classification #
QW 601
Previous Indexing
Blood Protein Disorders (1966-1975)
Immunoglobulins (1970-1975)
specific immunoglobulin (1966-1975)
Public MeSH Note
76; was see under GLOBULINS 1963-65
History Note
76; was see under GLOBULINS 1963-65
Date Established
1976/01/01
Date of Entry
1975/07/25
Revision Date
2020/05/27
Paraproteins Preferred
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