- Concept UI
- M0009095
- Scope Note
- Genes encoding the different subunits of the IMMUNOGLOBULINS, for example the IMMUNOGLOBULIN LIGHT CHAIN GENES and the IMMUNOGLOBULIN HEAVY CHAIN GENES. The heavy and light immunoglobulin genes are present as gene segments in the germline cells. The completed genes are created when the segments are shuffled and assembled (B-LYMPHOCYTE GENE REARRANGEMENT) during B-LYMPHOCYTE maturation. The gene segments of the human light and heavy chain germline genes are symbolized V (variable), J (joining) and C (constant). The heavy chain germline genes have an additional segment D (diversity).
- Terms
-
Genes, Immunoglobulin
Preferred Term
Term UI
T017507
Date01/01/1999
LexicalTag
NON
ThesaurusID
NLM (1988)
-
Genes, Ig
Term UI
T017508
Date05/11/1987
LexicalTag
NON
ThesaurusID
UNK (19XX)
-
Immunoglobulin Genes
Term UI
T017506
Date05/21/1991
LexicalTag
NON
ThesaurusID
NLM (1992)