MeSH Browser

MeSH Heading: Genes, MDR
Tree Number(s): G05.360.340.024.340.361; G05.360.340.024.340.645.500
Unique ID: D019450
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D019450
Scope Note: Genes for MEMBRANE TRANSPORT PROTEINS that confer resistance to toxic compounds. Several superfamilies of these multidrug export proteins are known and found in both prokaryotes and eukaryotes.
Entry Term(s): MDR Genes; Multidrug Efflux Pump Genes; Multidrug Resistance Gene
Previous Indexing: Drug Resistance (1986-1994); Drug Resistance, Multiple (1995-1996); Multigene Family (1989-1996)
See Also: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Resistance, Multiple
Public MeSH Note: 97
History Note: 97
Date Established: 1997/01/01
Date of Entry: 1996/06/13
Revision Date: 2018/07/16

Allowable Qualifiers: drug effects (DE)

genetics (GE)

immunology (IM)

physiology (PH)

radiation effects (RE)

Genetic Phenomena [G05]
- Genetic Structures [G05.360]
  - Genome [G05.360.340]
    - Genome Components [G05.360.340.024]
      - Genes [G05.360.340.024.340]
        
        Alleles [G05.360.340.024.340.030]
        
        Gene Components [G05.360.340.024.340.137]
        
        Genes, cdc [G05.360.340.024.340.220]
        
        Genes, Chloroplast [G05.360.340.024.340.225]
        
        Genes, Developmental [G05.360.340.024.340.230]
        
        Genes, Dominant [G05.360.340.024.340.240]
        
        Genes, Duplicate [G05.360.340.024.340.250]
        
        Genes, Essential [G05.360.340.024.340.270]
        
        Genes, Helminth [G05.360.340.024.340.310]
        
        Genes, Immediate-Early [G05.360.340.024.340.330]
        
        Genes, Immunoglobulin [G05.360.340.024.340.335]
        
        Genes, Insect [G05.360.340.024.340.340]
        
        Genes, Lethal [G05.360.340.024.340.350]
        
        Genes, MDR [G05.360.340.024.340.361]
        
        Genes, Microbial [G05.360.340.024.340.364]
        
        Genes, Mitochondrial [G05.360.340.024.340.365]
        
        Genes, Modifier [G05.360.340.024.340.370]
        
        Genes, Neoplasm [G05.360.340.024.340.375]
        
        Genes, Overlapping [G05.360.340.024.340.385]
        
        Genes, Plant [G05.360.340.024.340.393]
        
        Genes, Protozoan [G05.360.340.024.340.396]
        
        Genes, RAG-1 [G05.360.340.024.340.400]
        
        Genes, Recessive [G05.360.340.024.340.415]
        
        Genes, Regulator [G05.360.340.024.340.425]
        
        Genes, Reporter [G05.360.340.024.340.435]
        
        Genes, sry [G05.360.340.024.340.450]
        
        Genes, Suppressor [G05.360.340.024.340.460]
        
        Genes, Synthetic [G05.360.340.024.340.465]
        
        Genes, T-Cell Receptor [G05.360.340.024.340.475]
        
        Genes, X-Linked [G05.360.340.024.340.500]
        
        Genes, Y-Linked [G05.360.340.024.340.515]
        
        Major Histocompatibility Complex [G05.360.340.024.340.610]
        
        Multigene Family [G05.360.340.024.340.645]
        
        Pseudogenes [G05.360.340.024.340.700]
        
        Transgenes [G05.360.340.024.340.825]

Genetic Phenomena [G05]
- Genetic Structures [G05.360]
  - Genome [G05.360.340]
    - Genome Components [G05.360.340.024]
      - Genes [G05.360.340.024.340]
        
        Multigene Family [G05.360.340.024.340.645]
        
        Genes, MDR [G05.360.340.024.340.645.500]
        
        Genes, rRNA [G05.360.340.024.340.645.750]

Genes, MDR Preferred

Concept UI: M0028939
Scope Note: Genes for MEMBRANE TRANSPORT PROTEINS that confer resistance to toxic compounds. Several superfamilies of these multidrug export proteins are known and found in both prokaryotes and eukaryotes.
Terms: Genes, MDR Preferred Term
Term UI T057989
Date01/01/1999
LexicalTag ACX
ThesaurusID NLM (1997); MDR Genes
Term UI T057988
Date03/07/1996
LexicalTag NON
ThesaurusID NLM (1997); Multidrug Resistance Gene
Term UI T057990
Date03/07/1996
LexicalTag NON
ThesaurusID NLM (1997); Multidrug Efflux Pump Genes
Term UI T749905
Date04/23/2009
LexicalTag NON
ThesaurusID NLM (2010)

Genes, MDR MeSH Descriptor Data 2025