MeSH Browser

MeSH Heading: Genes, Immediate-Early
Tree Number(s): G05.360.340.024.340.330; G05.360.340.024.340.364.875.345; G05.360.340.358.024.875.345; G05.360.340.358.840.500.345
Unique ID: D017781
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D017781
Annotation: genes showing rapid & transient expression in absence of protein synthesis: read MeSH definition for history of "immediate-early"
Scope Note: Genes that show rapid and transient expression in the absence of de novo protein synthesis. The term was originally used exclusively for viral genes where immediate-early referred to transcription immediately following virus integration into the host cell. It is also used to describe cellular genes which are expressed immediately after resting cells are stimulated by extracellular signals such as growth factors and neurotransmitters.
Entry Term(s): Immediate Early Gene; Immediate-Early Gene; Immediate-Early Genes
Previous Indexing: Genes, Viral (1980-1993); specific genes (1972-1993)
See Also: Immediate-Early Proteins
Public MeSH Note: 94
History Note: 94
Date Introduced: 1994/01/01
Last Updated: 2020/05/27

Allowable Qualifiers: drug effects (DE)

ethics (ES)

genetics (GE)

immunology (IM)

physiology (PH)

radiation effects (RE)

Genetic Phenomena [G05]
- Genetic Structures [G05.360]
  - Genome [G05.360.340]
    - Genome Components [G05.360.340.024]
      - Genes [G05.360.340.024.340]
        
        Alleles [G05.360.340.024.340.030]
        
        Gene Components [G05.360.340.024.340.137]
        
        Genes, cdc [G05.360.340.024.340.220]
        
        Genes, Chloroplast [G05.360.340.024.340.225]
        
        Genes, Developmental [G05.360.340.024.340.230]
        
        Genes, Dominant [G05.360.340.024.340.240]
        
        Genes, Duplicate [G05.360.340.024.340.250]
        
        Genes, Essential [G05.360.340.024.340.270]
        
        Genes, Helminth [G05.360.340.024.340.310]
        
        Genes, Immediate-Early [G05.360.340.024.340.330]
        
        Genes, Immunoglobulin [G05.360.340.024.340.335]
        
        Genes, Insect [G05.360.340.024.340.340]
        
        Genes, Lethal [G05.360.340.024.340.350]
        
        Genes, MDR [G05.360.340.024.340.361]
        
        Genes, Microbial [G05.360.340.024.340.364]
        
        Genes, Mitochondrial [G05.360.340.024.340.365]
        
        Genes, Modifier [G05.360.340.024.340.370]
        
        Genes, Neoplasm [G05.360.340.024.340.375]
        
        Genes, Overlapping [G05.360.340.024.340.385]
        
        Genes, Plant [G05.360.340.024.340.393]
        
        Genes, Protozoan [G05.360.340.024.340.396]
        
        Genes, RAG-1 [G05.360.340.024.340.400]
        
        Genes, Recessive [G05.360.340.024.340.415]
        
        Genes, Regulator [G05.360.340.024.340.425]
        
        Genes, Reporter [G05.360.340.024.340.435]
        
        Genes, sry [G05.360.340.024.340.450]
        
        Genes, Suppressor [G05.360.340.024.340.460]
        
        Genes, Synthetic [G05.360.340.024.340.465]
        
        Genes, T-Cell Receptor [G05.360.340.024.340.475]
        
        Genes, X-Linked [G05.360.340.024.340.500]
        
        Genes, Y-Linked [G05.360.340.024.340.515]
        
        Major Histocompatibility Complex [G05.360.340.024.340.610]
        
        Multigene Family [G05.360.340.024.340.645]
        
        Pseudogenes [G05.360.340.024.340.700]
        
        Transgenes [G05.360.340.024.340.825]

Genetic Phenomena [G05]
- Genetic Structures [G05.360]
  - Genome [G05.360.340]
    - Genome Components [G05.360.340.024]
      - Genes [G05.360.340.024.340]
        
        Genes, Microbial [G05.360.340.024.340.364]
        
        Genes, Viral [G05.360.340.024.340.364.875]
        
        Genes, env [G05.360.340.024.340.364.875.172]
        
        Genes, gag [G05.360.340.024.340.364.875.258]
        
        Genes, Immediate-Early [G05.360.340.024.340.364.875.345]
        
        Genes, Intracisternal A-Particle [G05.360.340.024.340.364.875.360]
        
        Genes, nef [G05.360.340.024.340.364.875.600]
        
        Genes, pol [G05.360.340.024.340.364.875.667]
        
        Genes, pX [G05.360.340.024.340.364.875.735]
        
        Genes, rev [G05.360.340.024.340.364.875.775]
        
        Genes, tat [G05.360.340.024.340.364.875.850]
        
        Genes, vif [G05.360.340.024.340.364.875.890]
        
        Genes, vpr [G05.360.340.024.340.364.875.897]
        
        Genes, vpu [G05.360.340.024.340.364.875.900]

Genetic Phenomena [G05]
- Genetic Structures [G05.360]
  - Genome [G05.360.340]
    - Genome, Microbial [G05.360.340.358]
      - Genes, Microbial [G05.360.340.358.024]
        
        Genes, Viral [G05.360.340.358.024.875]
        
        Genes, env [G05.360.340.358.024.875.172]
        
        Genes, gag [G05.360.340.358.024.875.258]
        
        Genes, Immediate-Early [G05.360.340.358.024.875.345]
        
        Genes, Intracisternal A-Particle [G05.360.340.358.024.875.360]
        
        Genes, nef [G05.360.340.358.024.875.600]
        
        Genes, pol [G05.360.340.358.024.875.667]
        
        Genes, pX [G05.360.340.358.024.875.735]
        
        Genes, rev [G05.360.340.358.024.875.775]
        
        Genes, tat [G05.360.340.358.024.875.850]
        
        Genes, vif [G05.360.340.358.024.875.890]
        
        Genes, vpr [G05.360.340.358.024.875.897]
        
        Genes, vpu [G05.360.340.358.024.875.900]

Genetic Phenomena [G05]
- Genetic Structures [G05.360]
  - Genome [G05.360.340]
    - Genome, Microbial [G05.360.340.358]
      - Genome, Viral [G05.360.340.358.840]
        
        Genes, Viral [G05.360.340.358.840.500]
        
        Genes, env [G05.360.340.358.840.500.172]
        
        Genes, gag [G05.360.340.358.840.500.258]
        
        Genes, Immediate-Early [G05.360.340.358.840.500.345]
        
        Genes, Intracisternal A-Particle [G05.360.340.358.840.500.360]
        
        Genes, nef [G05.360.340.358.840.500.600]
        
        Genes, pol [G05.360.340.358.840.500.667]
        
        Genes, pX [G05.360.340.358.840.500.735]
        
        Genes, rev [G05.360.340.358.840.500.775]
        
        Genes, tat [G05.360.340.358.840.500.850]
        
        Genes, vif [G05.360.340.358.840.500.890]
        
        Genes, vpr [G05.360.340.358.840.500.897]
        
        Genes, vpu [G05.360.340.358.840.500.900]

Genes, Immediate-Early Preferred

Concept UI: M0026872
Scope Note: Genes that show rapid and transient expression in the absence of de novo protein synthesis. The term was originally used exclusively for viral genes where immediate-early referred to transcription immediately following virus integration into the host cell. It is also used to describe cellular genes which are expressed immediately after resting cells are stimulated by extracellular signals such as growth factors and neurotransmitters.
Terms: Genes, Immediate-Early Preferred Term
Term UI T053196
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1994); Immediate-Early Genes
Term UI T053195
Date10/21/1992
LexicalTag NON
ThesaurusID NLM (1994); Immediate-Early Gene
Term UI T001005256
Date01/13/2020
LexicalTag NON
ThesaurusID NLM (2021); Immediate Early Gene
Term UI T001005257
Date01/13/2020
LexicalTag NON
ThesaurusID NLM (2021)

Genes, Immediate-Early MeSH Descriptor Data 2026