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A negatively-charged extracellular matrix protein that plays a role in the regulation of BONE metabolism and a variety of other biological functions. Cell signaling by osteopontin may occur through a cell adhesion sequence that recognizes INTEGRIN ALPHA-V BETA-3.
Entry Term(s)
Bone Sialoprotein 1
Bone Sialoprotein I
Secreted Phosphoprotein 1
Sialoprotein 1
Uropontin
Registry Numbers
106441-73-0
0
Public MeSH Note
2007; OSTEOPONTIN was indexed under SIALOGLYCOPROTEINS 1987-2006
A negatively-charged extracellular matrix protein that plays a role in the regulation of BONE metabolism and a variety of other biological functions. Cell signaling by osteopontin may occur through a cell adhesion sequence that recognizes INTEGRIN ALPHA-V BETA-3.