MeSH Browser

MeSH Heading: Leukemia Inhibitory Factor
Tree Number(s): D12.644.276.374.470; D12.776.467.374.470; D23.529.374.470
Unique ID: D053605
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D053605
Scope Note: An INTERLEUKIN-6 related cytokine that exhibits pleiotrophic effects on many physiological systems that involve cell proliferation, differentiation, and survival. Leukemia inhibitory factor binds to and acts through the lif receptor.
Entry Term(s): AM424; Cholinergic Differentiation Factor; D Factor (Leukemia Inhibitory Factor); Differentiation-Stimulating Factor; Emfilermin; Myeloid Differentiation-Stimulating Factor
Public MeSH Note: 2007; LEUKEMIA INHIBITORY FACTOR was indexed under INTERLEUKIN-6 2004-2006 and under GROWTH INHIBITORS & LYMPHOKINES 1988-2003, & under GLYCOPROTEINS 1980-1986
History Note: 2007(1980)
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2016/07/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0097307
Scope Note: An INTERLEUKIN-6 related cytokine that exhibits pleiotrophic effects on many physiological systems that involve cell proliferation, differentiation, and survival. Leukemia inhibitory factor binds to and acts through the lif receptor.
Terms: Leukemia Inhibitory Factor Preferred Term
Term UI T127307
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007); Cholinergic Differentiation Factor
Term UI T127299
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007); Differentiation-Stimulating Factor
Term UI T127302
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007); Myeloid Differentiation-Stimulating Factor
Term UI T127309
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007); D Factor (Leukemia Inhibitory Factor)
Term UI T653463
Date09/29/2005
LexicalTag NON
ThesaurusID NLM (2007)

Leukemia Inhibitory Factor MeSH Descriptor Data 2025