- Concept UI
- M000628883
- Registry Numbers
- 0
- Scope Note
- A protein family characterized by a highly conserved N-terminus and four to six transmembrane helices; they function as bicarbonate permeable, calcium-activated chloride channels. Bestrophin-1 (BEST-1) and bestrophin-2 are highly expressed in human RETINAL PIGMENT EPITHELIUM cells and mutations in the BEST-1 gene are associated with VITELLIFORM MACULAR DYSTROPHY, TYPE 2.
- Terms
-
Bestrophins
Preferred Term
Term UI
T000919923
Date03/24/2017
LexicalTag
NON
ThesaurusID
NLM (2018)
-
Bestrophin
Term UI
T001089767
Date10/13/2020
LexicalTag
NON
ThesaurusID
NLM (2022)
-
Bestrophin Family
Term UI
T000919924
Date03/24/2017
LexicalTag
NON
ThesaurusID
NLM (2018)
-
Bestrophin Proteins
Term UI
T000919928
Date03/24/2017
LexicalTag
NON
ThesaurusID
NLM (2018)