MeSH Browser

MeSH Heading: Receptors, Glycine
Tree Number(s): D12.776.157.530.400.175.781; D12.776.157.530.400.400.100.200; D12.776.543.550.450.175.781; D12.776.543.550.450.500.100.200; D12.776.543.585.400.175.781; D12.776.543.585.400.500.100.200; D12.776.543.750.130.625; D12.776.543.750.720.200.470
Unique ID: D018009
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D018009
Scope Note: Cell surface receptors that bind GLYCINE with high affinity and trigger intracellular changes which influence the behavior of cells. Glycine receptors in the CENTRAL NERVOUS SYSTEM have an intrinsic chloride channel. GlyA receptor is sensitive to STRYCHNINE and localized in the post-synaptic membrane of inhibitory glycinergic neurons. GlyB receptor is insensitive to strychnine and associated with the excitatory NMDA receptor.
Entry Version: RECEPT GLYCINE
Entry Term(s): Excitatory Glycine Receptors; GlyA Receptors; GlyB Receptors; Glycine A Receptors; Glycine B Receptors; Glycine Receptor; Glycine Receptor alpha1; Glycine Receptors; Inhibitory Glycine Receptor; SIG Receptor; Strychnine-Insensitive Glycine Receptor; Strychnine-Sensitive Glycine Receptor
Registry Numbers: 0
Previous Indexing: Receptors, Cell Surface (1981-1984); Receptors, Neurotransmitter (1985-1993)
See Also: Glycine Plasma Membrane Transport Proteins
Public MeSH Note: 1994; was GLYCINE RECEPTOR (NM) 1981-1993; for GLYCINE RECEPTOR ALPHA1 see under RECEPTORS, GLYCINE 1995-2020; for GLYCINE RECEPTOR ALPHA1 see under RECEPTORS, GLYCINE 1997-2020
History Note: 1994; was GLYCINE RECEPTOR (NM) 1981-1993; for GLYCINE RECEPTOR ALPHA1 was under RECEPTORS, GLYCINE 1995-2020; for GLYCINE RECEPTOR ALPHA1 was under RECEPTORS, GLYCINE 1997-2020
Date Established: 1994/01/01
Date of Entry: 1993/06/21
Revision Date: 2021/02/09

Allowable Qualifiers: administration & dosage (AD)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - Membrane Transport Proteins [D12.776.157.530]
      - Ion Channels [D12.776.157.530.400]
        
        Chloride Channels [D12.776.157.530.400.175]
        
        Anoctamins [D12.776.157.530.400.175.032]
        
        Bestrophins [D12.776.157.530.400.175.063]
        
        CLC-2 Chloride Channels [D12.776.157.530.400.175.094]
        
        Cystic Fibrosis Transmembrane Conductance Regulator [D12.776.157.530.400.175.125]
        
        Receptors, GABA-A [D12.776.157.530.400.175.562]
        
        Receptors, Glycine [D12.776.157.530.400.175.781]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - Membrane Transport Proteins [D12.776.157.530]
      - Ion Channels [D12.776.157.530.400]
        
        Ligand-Gated Ion Channels [D12.776.157.530.400.400]
        
        Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.157.530.400.400.100]
        
        Receptors, GABA-A [D12.776.157.530.400.400.100.100]
        
        Receptors, Glycine [D12.776.157.530.400.400.100.200]
        
        Receptors, Nicotinic [D12.776.157.530.400.400.100.500]
        
        Receptors, Serotonin, 5-HT3 [D12.776.157.530.400.400.100.700]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Glycoproteins [D12.776.543.550]
      - Ion Channels [D12.776.543.550.450]
        
        Chloride Channels [D12.776.543.550.450.175]
        
        Anoctamins [D12.776.543.550.450.175.032]
        
        Bestrophins [D12.776.543.550.450.175.063]
        
        CLC-2 Chloride Channels [D12.776.543.550.450.175.094]
        
        Cystic Fibrosis Transmembrane Conductance Regulator [D12.776.543.550.450.175.125]
        
        Receptors, GABA-A [D12.776.543.550.450.175.562]
        
        Receptors, Glycine [D12.776.543.550.450.175.781]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Glycoproteins [D12.776.543.550]
      - Ion Channels [D12.776.543.550.450]
        
        Ligand-Gated Ion Channels [D12.776.543.550.450.500]
        
        Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.550.450.500.100]
        
        Receptors, GABA-A [D12.776.543.550.450.500.100.100]
        
        Receptors, Glycine [D12.776.543.550.450.500.100.200]
        
        Receptors, Nicotinic [D12.776.543.550.450.500.100.500]
        
        Receptors, Serotonin, 5-HT3 [D12.776.543.550.450.500.100.700]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Transport Proteins [D12.776.543.585]
      - Ion Channels [D12.776.543.585.400]
        
        Chloride Channels [D12.776.543.585.400.175]
        
        Anoctamins [D12.776.543.585.400.175.032]
        
        Bestrophins [D12.776.543.585.400.175.063]
        
        CLC-2 Chloride Channels [D12.776.543.585.400.175.094]
        
        Cystic Fibrosis Transmembrane Conductance Regulator [D12.776.543.585.400.175.125]
        
        Receptors, GABA-A [D12.776.543.585.400.175.562]
        
        Receptors, Glycine [D12.776.543.585.400.175.781]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Transport Proteins [D12.776.543.585]
      - Ion Channels [D12.776.543.585.400]
        
        Ligand-Gated Ion Channels [D12.776.543.585.400.500]
        
        Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.585.400.500.100]
        
        Receptors, GABA-A [D12.776.543.585.400.500.100.100]
        
        Receptors, Glycine [D12.776.543.585.400.500.100.200]
        
        Receptors, Nicotinic [D12.776.543.585.400.500.100.500]
        
        Receptors, Serotonin, 5-HT3 [D12.776.543.585.400.500.100.700]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.750.130]
        
        Receptors, GABA-A [D12.776.543.750.130.500]
        
        Receptors, Glycine [D12.776.543.750.130.625]
        
        Receptors, Nicotinic [D12.776.543.750.130.687]
        
        Receptors, Serotonin, 5-HT3 [D12.776.543.750.130.750]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Neurotransmitter [D12.776.543.750.720]
        
        Receptors, Amino Acid [D12.776.543.750.720.200]
        
        Receptors, GABA [D12.776.543.750.720.200.300]
        
        Receptors, Glutamate [D12.776.543.750.720.200.450]
        
        Receptors, Glycine [D12.776.543.750.720.200.470]

Receptors, Glycine Preferred

Concept UI: M0027191
Registry Numbers: 0
Scope Note: Cell surface receptors that bind GLYCINE with high affinity and trigger intracellular changes which influence the behavior of cells. Glycine receptors in the CENTRAL NERVOUS SYSTEM have an intrinsic chloride channel. GlyA receptor is sensitive to STRYCHNINE and localized in the post-synaptic membrane of inhibitory glycinergic neurons. GlyB receptor is insensitive to strychnine and associated with the excitatory NMDA receptor.
Terms: Receptors, Glycine Preferred Term
Term UI T053834
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1994); Glycine Receptor
Term UI T053832
Date12/16/1992
LexicalTag NON
ThesaurusID NLM (1994); Glycine Receptors
Term UI T053833
Date12/16/1992
LexicalTag NON
ThesaurusID NLM (1994)

Glycine Receptor alpha1 Narrower

Strychnine-Sensitive Glycine Receptor Narrower

Concept UI: M000681297
Registry Numbers: 0
Terms: Strychnine-Sensitive Glycine Receptor Preferred Term
Term UI T001007398
Date02/11/2020
LexicalTag NON
ThesaurusID NLM (2021); Inhibitory Glycine Receptor
Term UI T001007399
Date02/11/2020
LexicalTag NON
ThesaurusID NLM (2021); Glycine A Receptors
Term UI T001007420
Date02/11/2020
LexicalTag NON
ThesaurusID NLM (2021); GlyA Receptors
Term UI T001007422
Date02/11/2020
LexicalTag ABX
ThesaurusID NLM (2021)

Strychnine-Insensitive Glycine Receptor Related

Concept UI: M000681299
Registry Numbers: 0
Terms: Strychnine-Insensitive Glycine Receptor Preferred Term
Term UI T001007432
Date02/11/2020
LexicalTag NON
ThesaurusID NLM (2021); SIG Receptor
Term UI T001007429
Date02/11/2020
LexicalTag ABX
ThesaurusID NLM (2021); Excitatory Glycine Receptors
Term UI T001007435
Date02/11/2020
LexicalTag NON
ThesaurusID NLM (2021); Glycine B Receptors
Term UI T001007424
Date02/11/2020
LexicalTag NON
ThesaurusID NLM (2021); GlyB Receptors
Term UI T001007425
Date02/11/2020
LexicalTag ABX
ThesaurusID NLM (2021)

Receptors, Glycine MeSH Descriptor Data 2025