MeSH Browser

MeSH Heading: Receptors, Serotonin, 5-HT3
Tree Number(s): D12.776.157.530.400.400.100.700; D12.776.543.550.450.500.100.700; D12.776.543.585.400.500.100.700; D12.776.543.750.130.750; D12.776.543.750.670.800.300; D12.776.543.750.720.850.300
Unique ID: D044406
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D044406
Scope Note: A subclass of serotonin receptors that form cation channels and mediate signal transduction by depolarizing the cell membrane. The cation channels are formed from 5 receptor subunits. When stimulated the receptors allow the selective passage of SODIUM; POTASSIUM; and CALCIUM.
Entry Version: RECEPT SEROTONIN 5 HT3
Entry Term(s): 5-HT3 Receptor; 5-Hydroxytryptamine-3 Receptor; Receptor, Serotonin 3; Receptor, Serotonin, 5-HT3 Subunit A; Receptor, Serotonin, 5-HT3 Subunit B; Receptor, Serotonin, 5-HT3 Subunit C; Receptor, Serotonin, 5-HT3 Subunit D; Receptor, Serotonin, 5-HT3 Subunit E; Receptor, Serotonin, 5-HT3A; Receptor, Serotonin, 5-HT3B; Receptor, Serotonin, 5-HT3C; Receptor, Serotonin, 5-HT3D; Receptor, Serotonin, 5-HT3E; Serotonin 3 Receptor; Serotonin 3 Receptors
Previous Indexing: Receptors, Serotonin (1995-2003)
Public MeSH Note: 2004; SEROTONIN 3 RECEPTOR (now RECEPTORS, SEROTONIN, 5-HT3) was indexed under RECEPTORS, SEROTONIN 1995-2003
History Note: 2004; use RECEPTORS, SEROTONIN, 5-HT3 (NM) 1995-2003
Entry Combination: agonists:Serotonin 5-HT3 Receptor Agonists; antagonists & inhibitors:Serotonin 5-HT3 Receptor Antagonists
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2016/07/01

Entry Combination: agonists:Serotonin 5-HT3 Receptor Agonists; antagonists & inhibitors:Serotonin 5-HT3 Receptor Antagonists
Allowable Qualifiers: administration & dosage (AD)

analysis (AN)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - Membrane Transport Proteins [D12.776.157.530]
      - Ion Channels [D12.776.157.530.400]
        
        Ligand-Gated Ion Channels [D12.776.157.530.400.400]
        
        Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.157.530.400.400.100]
        
        Receptors, GABA-A [D12.776.157.530.400.400.100.100]
        
        Receptors, Glycine [D12.776.157.530.400.400.100.200]
        
        Receptors, Nicotinic [D12.776.157.530.400.400.100.500]
        
        Receptors, Serotonin, 5-HT3 [D12.776.157.530.400.400.100.700]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Glycoproteins [D12.776.543.550]
      - Ion Channels [D12.776.543.550.450]
        
        Ligand-Gated Ion Channels [D12.776.543.550.450.500]
        
        Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.550.450.500.100]
        
        Receptors, GABA-A [D12.776.543.550.450.500.100.100]
        
        Receptors, Glycine [D12.776.543.550.450.500.100.200]
        
        Receptors, Nicotinic [D12.776.543.550.450.500.100.500]
        
        Receptors, Serotonin, 5-HT3 [D12.776.543.550.450.500.100.700]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Transport Proteins [D12.776.543.585]
      - Ion Channels [D12.776.543.585.400]
        
        Ligand-Gated Ion Channels [D12.776.543.585.400.500]
        
        Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.585.400.500.100]
        
        Receptors, GABA-A [D12.776.543.585.400.500.100.100]
        
        Receptors, Glycine [D12.776.543.585.400.500.100.200]
        
        Receptors, Nicotinic [D12.776.543.585.400.500.100.500]
        
        Receptors, Serotonin, 5-HT3 [D12.776.543.585.400.500.100.700]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.750.130]
        
        Receptors, GABA-A [D12.776.543.750.130.500]
        
        Receptors, Glycine [D12.776.543.750.130.625]
        
        Receptors, Nicotinic [D12.776.543.750.130.687]
        
        Receptors, Serotonin, 5-HT3 [D12.776.543.750.130.750]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Biogenic Amine [D12.776.543.750.670]
        
        Receptors, Serotonin [D12.776.543.750.670.800]
        
        Receptors, Serotonin, 5-HT1 [D12.776.543.750.670.800.100]
        
        Receptors, Serotonin, 5-HT2 [D12.776.543.750.670.800.200]
        
        Receptors, Serotonin, 5-HT3 [D12.776.543.750.670.800.300]
        
        Receptors, Serotonin, 5-HT4 [D12.776.543.750.670.800.400]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Neurotransmitter [D12.776.543.750.720]
        
        Receptors, Serotonin [D12.776.543.750.720.850]
        
        Receptors, Serotonin, 5-HT1 [D12.776.543.750.720.850.100]
        
        Receptors, Serotonin, 5-HT2 [D12.776.543.750.720.850.200]
        
        Receptors, Serotonin, 5-HT3 [D12.776.543.750.720.850.300]
        
        Receptors, Serotonin, 5-HT4 [D12.776.543.750.720.850.400]

Receptors, Serotonin, 5-HT3 Preferred

Concept UI: M0244242
Scope Note: A subclass of serotonin receptors that form cation channels and mediate signal transduction by depolarizing the cell membrane. The cation channels are formed from 5 receptor subunits. When stimulated the receptors allow the selective passage of SODIUM; POTASSIUM; and CALCIUM.
Terms: Receptors, Serotonin, 5-HT3 Preferred Term
Term UI T530882
Date01/24/2003
LexicalTag ABX
ThesaurusID NLM (2004); 5-HT3 Receptor
Term UI T274242
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2004); 5-Hydroxytryptamine-3 Receptor
Term UI T274244
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Receptor, Serotonin 3
Term UI T274245
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Serotonin 3 Receptors
Term UI T274246
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Serotonin 3 Receptor
Term UI T274247
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004)

Receptor, Serotonin, 5-HT3 Subunit A Narrower

Receptor, Serotonin, 5-HT3 Subunit B Narrower

Receptor, Serotonin, 5-HT3 Subunit C Narrower

Receptor, Serotonin, 5-HT3 Subunit D Narrower

Receptor, Serotonin, 5-HT3 Subunit E Narrower

Receptors, Serotonin, 5-HT3 MeSH Descriptor Data 2025