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Receptors, Nicotinic MeSH Descriptor Data 2026


MeSH Heading
Receptors, Nicotinic
Tree Number(s)
D12.776.157.530.400.400.100.500
D12.776.543.550.450.500.100.500
D12.776.543.585.400.500.100.500
D12.776.543.750.130.687
D12.776.543.750.720.360.550
Unique ID
D011978
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D011978
Scope Note
One of the two major classes of cholinergic receptors. Nicotinic receptors were originally distinguished by their preference for NICOTINE over MUSCARINE. They are generally divided into muscle-type and neuronal-type (previously ganglionic) based on pharmacology, and subunit composition of the receptors.
Entry Version
RECEPT NICOTINIC
Entry Term(s)
Cholinergic Receptor, Nicotinic, alpha Polypeptide 3
Neuronal Acetylcholine Receptor Subunit alpha-3
Nicotinic Acetylcholine Receptor
Nicotinic Acetylcholine Receptor alpha4 Subunit
Nicotinic Acetylcholine Receptors
Nicotinic Receptor
Nicotinic Receptor Subunit alpha3
Nicotinic Receptor alpha3
Nicotinic Receptor alpha4
Nicotinic Receptor beta2
Nicotinic Receptors
Receptor, Nicotinic Acetylcholine beta-2
beta2 Nicotinic Acetylcholine Receptor
nAChR alpha 4
nAChR alpha3
nAChR alpha4
nAChR beta2
Registry Numbers
0
NLM Classification #
WL 102.8
Previous Indexing
Acetylcholine (1966-1976)
Nicotine (1974-1976)
Receptors, Cholinergic (1971-1976)
Receptors, Drug (1968-1976)
Public MeSH Note
2026; use RECEPTORS, CHOLINERGIC 1977-1983; for NICOTINIC RECEPTOR ALPHA3 see NICOTINIC RECEPTOR SUBUNIT ALPHA3(NM) 1997-2025; for NICOTINIC RECEPTOR ALPHA4 see NICOTINIC RECEPTOR ALPHA4 SUBUNIT(NM) 1997-2025; for NICOTINIC RECEPTOR BETA2 see NICOTINIC RECEPTOR BETA2 (NM) 2001-2025
History Note
2026(1977); see RECEPTORS, CHOLINERGIC 1977-1983
Entry Combination
agonists:Nicotinic Agonists
antagonists & inhibitors:Nicotinic Antagonists
Date Introduced
1984/01/01
Last Updated
2026/01/01
Receptors, Nicotinic Preferred
Nicotinic Receptor alpha4 Narrower
Nicotinic Receptor alpha3 Narrower
Nicotinic Receptor beta2 Narrower
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