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Complement C1 Inhibitor Protein MeSH Descriptor Data 2023


MeSH Heading
Complement C1 Inhibitor Protein
Tree Number(s)
D12.644.861.140.500
D12.776.124.486.274.920.250.500
D12.776.395.320
D12.776.872.140.500
Unique ID
D050718
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D050718
Annotation
do not confuse with COMPLEMENT C1 INACTIVATOR PROTEINS
Scope Note
An endogenous 105-kDa plasma glycoprotein produced primarily by the LIVER and MONOCYTES. It inhibits a broad spectrum of proteases, including the COMPLEMENT C1R and the COMPLEMENT C1S proteases of the CLASSICAL COMPLEMENT PATHWAY, and the MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES. C1-INH-deficient individuals suffer from HEREDITARY ANGIOEDEMA TYPES I AND II.
Entry Version
C 1 INH
Entry Term(s)
C1 Esterase Inhibitor
C1-INH Protein
C1-Inhibitor Protein
Complement C1-Inhibitor Protein
Plasma Protease C1 Inhibitor
SERPING1
Serpin Family G Member 1
Serpin G1
Pharm Action
Complement Inactivating Agents
Registry Number
0
Previous Indexing
Complement C1 Inactivator Proteins (1970-2005)
Public MeSH Note
2006; for C1 ESTERASE INHIBITOR see COMPLEMENT C1 INACTIVATOR PROTEINS 1979-2005
History Note
2006; for C1 ESTERASE INHIBITOR use COMPLEMENT C1 INACTIVATOR PROTEINS 1970-2005
Entry Combination
deficiency:Hereditary Angioedema Types I and II
Date Established
2006/01/01
Date of Entry
2005/06/30
Revision Date
2021/03/04
Complement C1 Inhibitor Protein Preferred
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