MeSH Browser

MeSH Heading: Somatomedins
Tree Number(s): D12.644.276.937; D12.776.124.862; D12.776.467.937; D23.529.937
Unique ID: D013002
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D013002
Scope Note: Insulin-like polypeptides made by the liver and some fibroblasts and released into the blood when stimulated by SOMATOTROPIN. They cause sulfate incorporation into collagen, RNA, and DNA synthesis, which are prerequisites to cell division and growth of the organism.
Entry Term(s): Insulin Like Growth Factor; Insulin Like Growth Factors; Insulin-Like Growth Factor; Insulin-Like Growth Factors; Somatomedin; Sulfation Factor
Registry Number: 0
NLM Classification #: QU 107
Previous Indexing: Blood Proteins (1966-1970); Sulfates/metabolism (1966-1970)
See Also: Receptors, Somatomedin
Public MeSH Note: 82; was SOMATOMEDIN 1973-81
Online Note: use SOMATOMEDINS to search SOMATOMEDIN 1973-81 & SULFATION FACTOR 1971-72 (as Prov 1971-72)
History Note: 82; was SOMATOMEDIN 1973-81, was SULFATION FACTOR 1971-72 (Prov)
Date Established: 1973/01/01
Date of Entry: 1999/01/01
Revision Date: 2021/06/30

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0020150
Registry Number: 0
Scope Note: Insulin-like polypeptides made by the liver and some fibroblasts and released into the blood when stimulated by SOMATOTROPIN. They cause sulfate incorporation into collagen, RNA, and DNA synthesis, which are prerequisites to cell division and growth of the organism.
Terms: Somatomedins Preferred Term
Term UI T038309
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1973); Insulin Like Growth Factors
Term UI T038306
Date06/14/1985
LexicalTag NON
ThesaurusID UNK (19XX); Insulin Like Growth Factor
Term UI T001089238
Date09/29/2020
LexicalTag NON
ThesaurusID NLM (2022); Somatomedin
Term UI T038308
Date05/12/1981
LexicalTag NON
ThesaurusID UNK (19XX); Sulfation Factor
Term UI T038310
Date03/30/1974
LexicalTag NON
ThesaurusID UNK (19XX); Insulin-Like Growth Factor
Term UI T000996314
Date11/14/2019
LexicalTag NON
ThesaurusID NLM (2021); Insulin-Like Growth Factors
Term UI T038307
Date06/14/1985
LexicalTag NON
ThesaurusID UNK (19XX)

Somatomedins MeSH Descriptor Data 2023