NLM Logo

Insulin-Like Growth Factor II MeSH Descriptor Data 2023


MeSH Heading
Insulin-Like Growth Factor II
Tree Number(s)
D12.644.276.937.420
D12.776.124.862.425
D12.776.467.937.420
D23.529.937.420
Unique ID
D007335
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D007335
Scope Note
A well-characterized neutral peptide believed to be secreted by the LIVER and to circulate in the BLOOD. It has growth-regulating, insulin-like and mitogenic activities. The growth factor has a major, but not absolute, dependence on SOMATOTROPIN. It is believed to be a major fetal growth factor in contrast to INSULIN-LIKE GROWTH FACTOR I, which is a major growth factor in adults.
Entry Term(s)
IGF-2
IGF-II
Insulin Like Growth Factor II
Insulin-Like Somatomedin Peptide II
Multiplication-Stimulating Activity
Multiplication-Stimulating Factor
Somatomedin A
Somatomedin MSA
Registry Number
67763-97-7
Related Numbers
9038-70-4
CAS Type 1 Name
Insulin-like growth factor II
NLM Classification #
QU 107
Previous Indexing
Blood Proteins (1966-1985)
Growth Substances (1966-1985)
Insulin (1966-1985)
Peptides (1966-1985)
Somatomedins (1973-1985)
Sulfation Factor (1971-1972)
See Also
Receptor, IGF Type 1
Receptor, IGF Type 2
Public MeSH Note
1991; see SOMATOMEDINS 1986-1990; SOMATOMEDIN A was indexed under INSULIN-LIKE GROWTH FACTOR II 1980-2004
History Note
1991(1986)
Date Established
1991/01/01
Date of Entry
1985/04/25
Revision Date
2006/07/05
Insulin-Like Growth Factor II Preferred
page delivered in 0.181s