MeSH Browser

MeSH Heading: Factor XI
Tree Number(s): D08.622.490; D12.776.124.125.425; D12.776.811.243.490; D23.119.425
Unique ID: D005172
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D005172
Annotation: a blood coag factor
Scope Note: Stable blood coagulation factor involved in the intrinsic pathway. The activated form XIa activates factor IX to IXa. Deficiency of factor XI is often called hemophilia C.
Entry Term(s): Blood Coagulation Factor XI; Coagulation Factor XI; Factor 11; Factor Eleven; Plasma Thromboplastin Antecedent
CAS Type 1 Name: Blood-coagulation factor XI
See Also: Coagulants
Public MeSH Note: 68
History Note: 68(64)
Entry Combination: deficiency:Factor XI Deficiency
Date Established: 1968/01/01
Date of Entry: 1999/01/01
Revision Date: 2019/05/30

Entry Combination: deficiency:Factor XI Deficiency
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0008156
Scope Note: Stable blood coagulation factor involved in the intrinsic pathway. The activated form XIa activates factor IX to IXa. Deficiency of factor XI is often called hemophilia C.
Terms: Factor XI Preferred Term
Term UI T015833
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1964); Factor 11
Term UI T000913565
Date01/04/2017
LexicalTag NON
ThesaurusID NLM (2018); Factor Eleven
Term UI T000913566
Date01/04/2017
LexicalTag NON
ThesaurusID NLM (2018); Plasma Thromboplastin Antecedent
Term UI T015834
Date03/30/1974
LexicalTag NON
ThesaurusID UNK (19XX); Coagulation Factor XI
Term UI T015835
Date07/31/1996
LexicalTag NON
ThesaurusID NLM (1998); Blood Coagulation Factor XI
Term UI T015836
Date02/11/1997
LexicalTag NON
ThesaurusID NLM (1998)

Factor XI MeSH Descriptor Data 2025