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von Willebrand Factor MeSH Descriptor Data 2021


MeSH Heading
von Willebrand Factor
Tree Number(s)
D12.776.124.125.920
D23.119.985
Unique ID
D014841
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D014841
Annotation
/ defic = VON WILLEBRAND DISEASE or specific type of Von Willebrand Disease
Scope Note
A high-molecular-weight plasma protein, produced by endothelial cells and megakaryocytes, that is part of the factor VIII/von Willebrand factor complex. The von Willebrand factor has receptors for collagen, platelets, and ristocetin activity as well as the immunologically distinct antigenic determinants. It functions in adhesion of platelets to collagen and hemostatic plug formation. The prolonged bleeding time in VON WILLEBRAND DISEASES is due to the deficiency of this factor.
Entry Version
VWF
Entry Term(s)
Factor VIII-Related Antigen
Factor VIIIR-Ag
Factor VIIIR-RCo
Plasma Factor VIII Complex
Ristocetin Cofactor
Ristocetin-Willebrand Factor
von Willebrand Protein
Registry Number
0
NLM Classification #
WH 310
Previous Indexing
Blood Coagulation Factors (1966-1974)
Blood Platelets (1966-1974)
von Willebrand's Disease (1966-1975)
See Also
Coagulants
von Willebrand Disease, Type 1
von Willebrand Disease, Type 2
von Willebrand Disease, Type 3
von Willebrand Diseases
Weibel-Palade Bodies
Public MeSH Note
86; was see under BLOOD COAGULATION FACTORS 1976-85
Online Note
use FACTOR VIII & ANTIGENS to search FACTOR VIII RELATED ANTIGEN 1977-89
History Note
86(76); was see under BLOOD COAGULATION FACTORS 1976-85; FACTOR VIII RELATED ANTIGEN, previously in the Supplementary Chemical File, was mapped to both FACTOR VIII & ANTIGENS 1977-89
Date Established
1986/01/01
Date of Entry
1975/07/25
Revision Date
2009/07/06
von Willebrand Factor Preferred
Plasma Factor VIII Complex Broader
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