MeSH Browser

MeSH Heading: Plasminogen Activator Inhibitor 1
Tree Number(s): D12.644.861.695.500; D12.776.124.125.640; D12.776.872.695.500; D23.119.832.500
Unique ID: D017395
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D017395
Scope Note: A member of the serpin family of proteins. It inhibits both the tissue-type and urokinase-type plasminogen activators.
Entry Version: PLASMINOGEN ACTIVATOR INHIB 1
Entry Term(s): PAI-1; SERPINE1 Protein; Serpin E1; Type 1 Plasminogen Activator Inhibitor
Pharm Action: Serine Proteinase Inhibitors
Previous Indexing: Plasminogen Inactivators (1990-1992)
Public MeSH Note: 93; PAI-1 was see PLASMINOGEN INACTIVATORS 1990-92
Online Note: use PLASMINOGEN INACTIVATORS to search PAI-1 1990-92
History Note: 93; PAI-1 was see PLASMINOGEN INACTIVATORS 1990-92
Date Established: 1993/01/01
Date of Entry: 1992/05/22
Revision Date: 2015/11/23

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0026409
Scope Note: A member of the serpin family of proteins. It inhibits both the tissue-type and urokinase-type plasminogen activators.
Terms: Plasminogen Activator Inhibitor 1 Preferred Term
Term UI T052012
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1993); SERPINE1 Protein
Term UI T000888723
Date10/30/2015
LexicalTag NON
ThesaurusID NLM (2017); PAI-1
Term UI T052010
Date03/20/1992
LexicalTag ABB
ThesaurusID NLM (1993); Type 1 Plasminogen Activator Inhibitor
Term UI T052011
Date03/20/1992
LexicalTag NON
ThesaurusID NLM (1993); Serpin E1
Term UI T734886
Date02/10/2009
LexicalTag NON
ThesaurusID NLM (2010)

Plasminogen Activator Inhibitor 1 MeSH Descriptor Data 2025