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Lupus Coagulation Inhibitor MeSH Descriptor Data 2022


MeSH Heading
Lupus Coagulation Inhibitor
Tree Number(s)
D12.776.124.486.485.114.323.210.600
D12.776.124.790.651.114.323.210.600
D12.776.377.715.548.114.323.210.600
D23.113.475
Unique ID
D016682
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016682
Scope Note
An antiphospholipid antibody found in association with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; and in a variety of other diseases as well as in healthy individuals. In vitro, the antibody interferes with the conversion of prothrombin to thrombin and prolongs the partial thromboplastin time. In vivo, it exerts a procoagulant effect resulting in thrombosis mainly in the larger veins and arteries. It further causes obstetrical complications, including fetal death and spontaneous abortion, as well as a variety of hematologic and neurologic complications.
Entry Version
LUPUS COAG INHIB
Entry Term(s)
Anticoagulant, Lupus
Coagulation Inhibitor, Lupus
Inhibitor, Lupus Coagulation
Lupus Anticoagulant
Pharm Action
Immunologic Factors
Registry Number
0
Previous Indexing
Autoantibodies (1966-1991)
Blood Coagulation Factors (1966-1991)
See Also
Antiphospholipid Syndrome
Public MeSH Note
92; LUPUS COAGULATION INHIBITOR was indexed under BLOOD COAGULATION FACTORS/immunology 1986-91 & BLOOD COAGULATION FACTORS/antagonists & inhibitors 1978-88
Online Note
use LUPUS COAGULATION INHIBITOR (NM) to search LUPUS COAGULATION INHIBITOR 1980-91
History Note
92; was LUPUS COAGULATION INHIBITOR (NM) 1978-91
Date Established
1992/01/01
Date of Entry
1991/07/12
Revision Date
2005/07/19
Lupus Coagulation Inhibitor Preferred
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