- Concept UI
- M0025416
- Registry Number
- 0
- Scope Note
- An antiphospholipid antibody found in association with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; and in a variety of other diseases as well as in healthy individuals. In vitro, the antibody interferes with the conversion of prothrombin to thrombin and prolongs the partial thromboplastin time. In vivo, it exerts a procoagulant effect resulting in thrombosis mainly in the larger veins and arteries. It further causes obstetrical complications, including fetal death and spontaneous abortion, as well as a variety of hematologic and neurologic complications.
- Terms
-
Lupus Coagulation Inhibitor
Preferred Term
Term UI
T049972
Date01/01/1999
LexicalTag
NON
ThesaurusID
NLM (1992)
-
Inhibitor, Lupus Coagulation
Term UI
T049971
Date01/31/1991
LexicalTag
NON
ThesaurusID
NLM (1992)
-
Coagulation Inhibitor, Lupus
Term UI
T049970
Date01/31/1991
LexicalTag
NON
ThesaurusID
NLM (1992)
-
Lupus Anticoagulant
Term UI
T049969
Date11/13/1990
LexicalTag
NON
ThesaurusID
NLM (1992)
-
Anticoagulant, Lupus
Term UI
T049968
Date12/02/1996
LexicalTag
NON
ThesaurusID
NLM (1998)