MeSH Browser

MeSH Heading: Proprotein Convertases
Tree Number(s): D08.811.277.656.837
Unique ID: D043484
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D043484
Scope Note: Proteolytic enzymes that are involved in the conversion of protein precursors such as peptide prohormones into PEPTIDE HORMONES. Some are ENDOPEPTIDASES, some are EXOPEPTIDASES.
Entry Term(s): POMC Convertase; POMC Enzyme; POMC-Converting Enzyme; Pro-Opiocortin Converting Enzyme; Pro-Opiocortin Converting Protease; Pro-Opiomelanocortin Converting Enzyme; Prohormone Convertase; Prohormone Convertases; Proopiomelanocortin Convertase; Proprotein Convertase; Proprotein Convertase, Subtilisin-Kexin Family; Proprotein Convertases, Subtilisin-Kexin Family; Subtilisin-Like Proprotein Convertases
Related Numbers: EC 3.4.21.-; EC 3.4.21.61; EC 3.4.23.17
Previous Indexing: Aspartic Endopeptidases (1994-2003); Peptide Peptidohydrolases (1982-1993); Subtilisins (2002-2003)
Public MeSH Note: 2004; PROPROTEIN COVERTASES was indexed under SUBSTILISINS 2002-2003; PRO-OPIOMELANOCORTIN CONVERTING ENZYME was indexed under ASPARTIC ENDOPEPTIDASES 1994-2003, under PEPTIDE PEPTIDOHYDROLASES 1982-1993
History Note: 2004; use PROPROTEIN CONVERTASES (NM) 2002-2003; for PRO-OPIOMELANOCORTIN CONVERTING ENZYME use PROPROTEIN CONVERTASES (NM) 1982-2003
Date Established: 2004/01/01
Date of Entry: 2003/07/22
Revision Date: 2016/06/30

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0103951
Terms: Pro-Opiomelanocortin Converting Enzyme Preferred Term
Term UI T133955
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); POMC Enzyme
Term UI T133940
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2004); POMC-Converting Enzyme
Term UI T133941
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); POMC Convertase
Term UI T133939
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2004); Pro-Opiocortin Converting Protease
Term UI T133946
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Proopiomelanocortin Convertase
Term UI T133952
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Pro-Opiocortin Converting Enzyme
Term UI T133945
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004)

Proprotein Convertases MeSH Descriptor Data 2025