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Carboxypeptidase B2 MeSH Descriptor Data 2022


MeSH Heading
Carboxypeptidase B2
Tree Number(s)
D08.811.277.656.350.245.125
D08.811.277.656.350.555.225
D08.811.277.656.675.555.225
D08.811.277.656.837.092
Unique ID
D025901
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D025901
Scope Note
A carboxypeptidase that removes C-terminal lysine or arginine from peptides and proteins. Carboxypeptidase B2 (CPB2) is released into the circulation as a proenzyme which is activated by the THROMBIN-THROMBOMODULIN complex. Activated CPB2 is involved in modulating a variety of processes by cleaving and inactivating various circulating proteins and peptides that are its substrates including FIBRIN; KININS; and ANAPHYLATOXINS.
Entry Term(s)
Arginine Carboxypeptidase
Carboxypeptidase B2, Plasma
Carboxypeptidase R
Carboxypeptidase U
Plasma Procarboxypeptidase B
Procarboxypeptidase U
Thrombin-Activatable Fibrinolysis Inhibitor
Thrombin-Activatable Fibrinolysis Inhibitor (TAFI)
Registry Number
EC 3.4.17.20
Previous Indexing
Carboxypeptidases (1979-2001)
Lysine Carboxypeptidase (1994-2001)
Public MeSH Note
2015; see CARBOXYPEPTIDASE U 2002-2014; CARBOXYPEPTIDASE U (NM) was indexed under CARBOXYPEPTIDASES 1994-2001; for ARGININE CARBOXYPEPTIDASE see LYSINE CARBOXYPEPTIDASE 1997-2001
History Note
2015 (2002); use CARBOXYPEPTIDASE U (NM) 1994-2001 and LYSINE CARBOXYPEPTIDASE 1997-2001
Date Established
2002/01/01
Date of Entry
2001/07/25
Revision Date
2014/06/06
Carboxypeptidase B2 Preferred
Procarboxypeptidase U Related
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