- Concept UI
- M0012373
- Registry Numbers
- EC 3.4.11.1
- Scope Note
- A zinc containing enzyme of the hydrolase class that catalyzes the removal of the N-terminal amino acid from most L-peptides, particularly those with N-terminal leucine residues but not those with N-terminal lysine or arginine residues. This occurs in tissue cell cytosol, with high activity in the duodenum, liver, and kidney. The activity of this enzyme is commonly assayed using a leucine arylamide chromogenic substrate such as leucyl beta-naphthylamide.
- Terms
-
Leucyl Aminopeptidase
Preferred Term
Term UI
T023624
Date01/01/1999
LexicalTag
NON
ThesaurusID
NLM (1965)
-
Cytosol Aminopeptidase
Term UI
T023619
Date12/30/1988
LexicalTag
NON
ThesaurusID
NLM (1990)
-
L-Leucylnaphthylamidase
Term UI
T023620
Date08/30/1982
LexicalTag
NON
ThesaurusID
UNK (19XX)
-
Leucine Aminopeptidase
Term UI
T023621
Date11/06/1997
LexicalTag
NON
ThesaurusID
NLM (1999)
-
Zinc-Manganese-Leucine Aminopeptidase
Term UI
T023622
Date11/29/1982
LexicalTag
NON
ThesaurusID
UNK (19XX)
-
Peptidase S
Term UI
T023623
Date12/08/1997
LexicalTag
NON
ThesaurusID
NLM (1999)