Carboxypeptidase H MeSH Descriptor Data 2025

MeSH Heading: Carboxypeptidase H
Tree Number(s): D08.811.277.656.350.245.167; D08.811.277.656.350.555.250; D08.811.277.656.675.555.250; D08.811.277.656.837.124
Unique ID: D043423
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D043423
Scope Note: A ZINC-containing exopeptidase primarily found in SECRETORY VESICLES of endocrine and neuroendocrine cells. It catalyzes the cleavage of C-terminal ARGININE or LYSINE residues from polypeptides and is active in processing precursors of PEPTIDE HORMONES and other bioactive peptides.
Entry Term(s): Carboxypeptidase E; Enkephalin Convertase; Enkephalin-Forming Carboxypeptidase; Enkephalin-Synthesizing Carboxypeptidase
Previous Indexing: Carboxypeptidases (1982-2003)
Public MeSH Note: 2004; CARBOXYPETIDASE H was indexed under CARBOXYPEPTIDASES 1982-2003
History Note: 2004; use CARBOXYPEPTIDASE H (NM) 1982-2003
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2013/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - Exopeptidases [D08.811.277.656.350]
        
        Carboxypeptidases [D08.811.277.656.350.245]
        
        Angiotensin-Converting Enzyme 2 [D08.811.277.656.350.245.042]
        
        Carboxypeptidase B [D08.811.277.656.350.245.083]
        
        Carboxypeptidase B2 [D08.811.277.656.350.245.125]
        
        Carboxypeptidase H [D08.811.277.656.350.245.167]
        
        Carboxypeptidases A [D08.811.277.656.350.245.250]
        
        Cathepsin A [D08.811.277.656.350.245.260]
        
        Cathepsin Z [D08.811.277.656.350.245.270]
        
        gamma-Glutamyl Hydrolase [D08.811.277.656.350.245.280]
        
        Glutamate Carboxypeptidase II [D08.811.277.656.350.245.400]
        
        Lysine Carboxypeptidase [D08.811.277.656.350.245.450]
        
        Muramoylpentapeptide Carboxypeptidase [D08.811.277.656.350.245.500]
        
        Serine-Type D-Ala-D-Ala Carboxypeptidase [D08.811.277.656.350.245.800]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - Exopeptidases [D08.811.277.656.350]
        
        Metalloexopeptidases [D08.811.277.656.350.555]
        
        CD13 Antigens [D08.811.277.656.350.555.100]
        
        Carboxypeptidase B [D08.811.277.656.350.555.200]
        
        Carboxypeptidase B2 [D08.811.277.656.350.555.225]
        
        Carboxypeptidase H [D08.811.277.656.350.555.250]
        
        Carboxypeptidases A [D08.811.277.656.350.555.350]
        
        Cystinyl Aminopeptidase [D08.811.277.656.350.555.400]
        
        Glutamate Carboxypeptidase II [D08.811.277.656.350.555.500]
        
        Glutamyl Aminopeptidase [D08.811.277.656.350.555.600]
        
        Leucyl Aminopeptidase [D08.811.277.656.350.555.700]
        
        Lysine Carboxypeptidase [D08.811.277.656.350.555.750]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - Metalloproteases [D08.811.277.656.675]
        
        Metalloexopeptidases [D08.811.277.656.675.555]
        
        CD13 Antigens [D08.811.277.656.675.555.100]
        
        Carboxypeptidase B [D08.811.277.656.675.555.200]
        
        Carboxypeptidase B2 [D08.811.277.656.675.555.225]
        
        Carboxypeptidase H [D08.811.277.656.675.555.250]
        
        Carboxypeptidases A [D08.811.277.656.675.555.350]
        
        Cystinyl Aminopeptidase [D08.811.277.656.675.555.400]
        
        Glutamate Carboxypeptidase II [D08.811.277.656.675.555.500]
        
        Glutamyl Aminopeptidase [D08.811.277.656.675.555.600]
        
        Leucyl Aminopeptidase [D08.811.277.656.675.555.700]
        
        Lysine Carboxypeptidase [D08.811.277.656.675.555.750]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - Proprotein Convertases [D08.811.277.656.837]
        
        Carboxypeptidase B [D08.811.277.656.837.061]
        
        Carboxypeptidase B2 [D08.811.277.656.837.092]
        
        Carboxypeptidase H [D08.811.277.656.837.124]
        
        Furin [D08.811.277.656.837.249]
        
        Proprotein Convertase 1 [D08.811.277.656.837.500]
        
        Proprotein Convertase 2 [D08.811.277.656.837.562]
        
        Proprotein Convertase 5 [D08.811.277.656.837.625]
        
        Proprotein Convertase 9 [D08.811.277.656.837.688]
        
        Renin [D08.811.277.656.837.750]

Carboxypeptidase H Preferred

Concept UI: M0108540
Scope Note: A ZINC-containing exopeptidase primarily found in SECRETORY VESICLES of endocrine and neuroendocrine cells. It catalyzes the cleavage of C-terminal ARGININE or LYSINE residues from polypeptides and is active in processing precursors of PEPTIDE HORMONES and other bioactive peptides.
Terms: Carboxypeptidase H Preferred Term
Term UI T138544
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Carboxypeptidase E
Term UI T138540
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Enkephalin Convertase
Term UI T138541
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Enkephalin-Forming Carboxypeptidase
Term UI T138542
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Enkephalin-Synthesizing Carboxypeptidase
Term UI T138543
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004)

page delivered in 0.153s