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Proprotein Convertase 9 MeSH Descriptor Data 2022


MeSH Heading
Proprotein Convertase 9
Tree Number(s)
D08.811.277.656.300.760.718
D08.811.277.656.837.688
D08.811.277.656.959.350.718
Unique ID
D000071449
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000071449
Scope Note
A proprotein convertase that is essential for CHOLESTEROL homeostasis. It binds to and is required for the lysosomal degradation of the LDL RECEPTOR (LDLR); the VLDL receptor, and the APOLIPOPROTEIN E RECEPTOR. It also regulates neuronal APOPTOSIS.
Entry Term(s)
NARC-1 Protein
Neural Apoptosis-Regulated Convertase 1
Proprotein Convertase, Subtilisin-Kexin Type 9
Registry Number
EC 3.4.21.-
Previous Indexing
Proprotein Convertases (2003-2016)
Serine Endopeptidases (2003-2016)
Public MeSH Note
2017
History Note
2017
Entry Combination
antagonists & inhibitors:PCSK9 Inhibitors
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2021/06/30
Proprotein Convertase 9 Preferred
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