MeSH Browser

MeSH Heading: Myeloblastin
Tree Number(s): D08.811.277.656.300.760.530; D08.811.277.656.959.350.530
Unique ID: D053146
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D053146
Scope Note: A polymorphonuclear leukocyte-derived serine protease that degrades proteins such as ELASTIN; FIBRONECTIN; LAMININ; VITRONECTIN; and COLLAGEN. It is named for its ability to control myeloid cell growth and differentiation.
Entry Term(s): Azurophil Granule Protein 7; C-ANCA Antigen; Leukocyte Proteinase 3; Myeloblastin, Human; N-Proteinase 4; Neutrophil Proteinase 3; Neutrophil Proteinase 3, Human; Neutrophil Proteinase 4; PRTN3 Gene Protein; Proteinase 3; Wegener Autoantigen
Previous Indexing: Serine Endopeptidases (1988-2006); Wegener Granulomatosis (1990-2006)
See Also: Granulomatosis with Polyangiitis
Public MeSH Note: 2007
History Note: 2007
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2009/07/06

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - Endopeptidases [D08.811.277.656.300]
        
        Serine Endopeptidases [D08.811.277.656.300.760]
        
        Acrosin [D08.811.277.656.300.760.030]
        
        Cathepsin G [D08.811.277.656.300.760.066]
        
        Chymases [D08.811.277.656.300.760.103]
        
        Chymotrypsin [D08.811.277.656.300.760.176]
        
        Complement Factor B [D08.811.277.656.300.760.198]
        
        Complement Factor D [D08.811.277.656.300.760.200]
        
        Complement Factor I [D08.811.277.656.300.760.210]
        
        Endopeptidase K [D08.811.277.656.300.760.247]
        
        Enteropeptidase [D08.811.277.656.300.760.284]
        
        Factor VIIa [D08.811.277.656.300.760.300]
        
        Factor IXa [D08.811.277.656.300.760.310]
        
        Factor Xa [D08.811.277.656.300.760.315]
        
        Factor XIa [D08.811.277.656.300.760.320]
        
        Factor XIIa [D08.811.277.656.300.760.324]
        
        Fibrinolysin [D08.811.277.656.300.760.330]
        
        Furin [D08.811.277.656.300.760.353]
        
        Granzymes [D08.811.277.656.300.760.397]
        
        High-Temperature Requirement A Serine Peptidase 1 [D08.811.277.656.300.760.420]
        
        High-Temperature Requirement A Serine Peptidase 2 [D08.811.277.656.300.760.431]
        
        Kallikreins [D08.811.277.656.300.760.442]
        
        Lactoferrin [D08.811.277.656.300.760.471]
        
        Mannose-Binding Protein-Associated Serine Proteases [D08.811.277.656.300.760.501]
        
        Myeloblastin [D08.811.277.656.300.760.530]
        
        Pancreatic Elastase [D08.811.277.656.300.760.560]
        
        Plasminogen Activators [D08.811.277.656.300.760.635]
        
        Prolyl Oligopeptidases [D08.811.277.656.300.760.637]
        
        Pronase [D08.811.277.656.300.760.638]
        
        Proprotein Convertase 1 [D08.811.277.656.300.760.640]
        
        Proprotein Convertase 2 [D08.811.277.656.300.760.646]
        
        Proprotein Convertase 5 [D08.811.277.656.300.760.648]
        
        Proprotein Convertase 9 [D08.811.277.656.300.760.718]
        
        Reelin Protein [D08.811.277.656.300.760.753]
        
        Subtilisins [D08.811.277.656.300.760.787]
        
        Thrombin [D08.811.277.656.300.760.855]
        
        Tissue Plasminogen Activator [D08.811.277.656.300.760.875]
        
        Trypsin [D08.811.277.656.300.760.895]
        
        Tryptases [D08.811.277.656.300.760.902]
        
        Urokinase-Type Plasminogen Activator [D08.811.277.656.300.760.910]
        
        Venombin A [D08.811.277.656.300.760.955]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - Serine Proteases [D08.811.277.656.959]
        
        Serine Endopeptidases [D08.811.277.656.959.350]
        
        Acrosin [D08.811.277.656.959.350.030]
        
        Cathepsin G [D08.811.277.656.959.350.066]
        
        Chymases [D08.811.277.656.959.350.103]
        
        Chymotrypsin [D08.811.277.656.959.350.176]
        
        Complement Factor B [D08.811.277.656.959.350.198]
        
        Complement Factor D [D08.811.277.656.959.350.200]
        
        Complement Factor I [D08.811.277.656.959.350.210]
        
        Endopeptidase K [D08.811.277.656.959.350.247]
        
        Enteropeptidase [D08.811.277.656.959.350.284]
        
        Factor VIIa [D08.811.277.656.959.350.300]
        
        Factor IXa [D08.811.277.656.959.350.310]
        
        Factor Xa [D08.811.277.656.959.350.315]
        
        Factor XIa [D08.811.277.656.959.350.320]
        
        Factor XIIa [D08.811.277.656.959.350.324]
        
        Fibrinolysin [D08.811.277.656.959.350.330]
        
        Furin [D08.811.277.656.959.350.353]
        
        Granzymes [D08.811.277.656.959.350.397]
        
        High-Temperature Requirement A Serine Peptidase 1 [D08.811.277.656.959.350.420]
        
        High-Temperature Requirement A Serine Peptidase 2 [D08.811.277.656.959.350.431]
        
        Kallikreins [D08.811.277.656.959.350.442]
        
        Lactoferrin [D08.811.277.656.959.350.471]
        
        Mannose-Binding Protein-Associated Serine Proteases [D08.811.277.656.959.350.501]
        
        Myeloblastin [D08.811.277.656.959.350.530]
        
        Pancreatic Elastase [D08.811.277.656.959.350.560]
        
        Plasminogen Activators [D08.811.277.656.959.350.635]
        
        Pronase [D08.811.277.656.959.350.638]
        
        Proprotein Convertase 1 [D08.811.277.656.959.350.640]
        
        Proprotein Convertase 2 [D08.811.277.656.959.350.646]
        
        Proprotein Convertase 5 [D08.811.277.656.959.350.648]
        
        Proprotein Convertase 9 [D08.811.277.656.959.350.718]
        
        Reelin Protein [D08.811.277.656.959.350.753]
        
        Subtilisins [D08.811.277.656.959.350.787]
        
        Thrombin [D08.811.277.656.959.350.855]
        
        Tissue Plasminogen Activator [D08.811.277.656.959.350.875]
        
        Trypsin [D08.811.277.656.959.350.895]
        
        Tryptases [D08.811.277.656.959.350.902]
        
        Urokinase-Type Plasminogen Activator [D08.811.277.656.959.350.910]
        
        Venombin A [D08.811.277.656.959.350.955]

Myeloblastin Preferred

Concept UI: M0161951
Scope Note: A polymorphonuclear leukocyte-derived serine protease that degrades proteins such as ELASTIN; FIBRONECTIN; LAMININ; VITRONECTIN; and COLLAGEN. It is named for its ability to control myeloid cell growth and differentiation.
Terms: Myeloblastin Preferred Term
Term UI T191956
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007); Neutrophil Proteinase 4
Term UI T191953
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007); Proteinase 3
Term UI T191955
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007); Wegener Autoantigen
Term UI T191950
Date01/01/1955
LexicalTag EPO
ThesaurusID NLM (2007); C-ANCA Antigen
Term UI T849692
Date09/27/2013
LexicalTag ABX
ThesaurusID NLM (2015); PRTN3 Gene Protein
Term UI T849693
Date09/27/2013
LexicalTag ABX
ThesaurusID NLM (2015); Azurophil Granule Protein 7
Term UI T191951
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007); Leukocyte Proteinase 3
Term UI T658635
Date11/17/2005
LexicalTag NON
ThesaurusID NLM (2007); Myeloblastin, Human
Term UI T658634
Date11/17/2005
LexicalTag NON
ThesaurusID NLM (2007); N-Proteinase 4
Term UI T191948
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007); Neutrophil Proteinase 3, Human
Term UI T658633
Date11/17/2005
LexicalTag NON
ThesaurusID NLM (2007); Neutrophil Proteinase 3
Term UI T191952
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007)

Myeloblastin MeSH Descriptor Data 2025