Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

NLM Logo

Prolyl Oligopeptidases MeSH Descriptor Data 2026


MeSH Heading
Prolyl Oligopeptidases
Tree Number(s)
D08.811.277.656.300.760.637
Unique ID
D000085822
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000085822
Scope Note
A family of serine proteases with specificity for proline-specific cleavage of peptides that are not longer than 30 amino acids. In humans it is broadly distributed in all tissues with higher activity found in the brain.
Entry Term(s)
Post-Proline Cleaving Enzyme
Post-Proline Endopeptidase
Proline Endopeptidase
Proline Specific Endopeptidase
Prolyl Endopeptidase
Prolyl Endopeptidase (Thiol-dependent)
Prolyl Endopeptidase I
Prolyl Oligopeptidase
Registry Numbers
EC 3.4.21.26
Related Numbers
72162-84-6
EC 3.4.21.26
OJQ0VJ822N
Public MeSH Note
2021; PROLYL OLIGOPEPTIDASES was indexed under SERINE ENDOPEPTIDASES 1988-2020; PEPTIDE PEPTIDOHYDROLASES 1980-1987; and under PROLINE 1977-1980
History Note
2021
Date Introduced
2021/01/01
Last Updated
2021/01/01
Prolyl Oligopeptidases Preferred
page delivered in 0.135s