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Angiotensin-Converting Enzyme 2 MeSH Descriptor Data 2023


MeSH Heading
Angiotensin-Converting Enzyme 2
Tree Number(s)
D08.811.277.656.350.245.042
Unique ID
D000085962
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000085962
Scope Note
A transmembrane glycoprotein with an extracellular catalytic domain which functions as a carboxypeptidase. It cleaves a single C-terminal residue from a distinct range of substrates. The catalytic efficiency is 400-fold higher with ANGIOTENSIN II as a substrate than with ANGIOTENSIN I. Angiotensin-converting enzyme 2 is also is a functional receptor for the spike glycoprotein (SPIKE PROTEIN, CORONAVIRUS) of the CORONAVIRUSES SARS-COV, SARS-COV2, and HCOV-NL63.
Entry Term(s)
ACE-Related Carboxypeptidase
ACE2 Angiotensin-Converting Enzyme Protein 2
ACE2 Enzyme
ACE2 Protein
Angiotensin Converting Enzyme 2
Angiotensin-Converting Enzyme-Related Carboxypeptidase
Registry Number
EC 3.4.17.23
Public MeSH Note
2021; ACE2 ENZYME was indexed as CARBOXYPEPTIDASES 2000-2006; and PEPTIDYL-DIPEPTIDASE A 2007-2020
History Note
2021 (2000)
Date Established
2021/01/01
Date of Entry
2020/07/07
Revision Date
2020/06/09
Angiotensin-Converting Enzyme 2 Preferred
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