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Pancreatitis-Associated Proteins MeSH Descriptor Data 2025


MeSH Heading
Pancreatitis-Associated Proteins
Tree Number(s)
D12.776.503.280.578
D23.050.285.733
D23.101.140.780
Unique ID
D000073718
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000073718
Scope Note
C-type lectins that restrict growth of bacteria in the intestinal epithelia and have bactericidal activity against gram-positive and gram-negative bacteria. They also regulate proliferation and differentiation of KERATINOCYTES following injury. Human pancreatitis-associated protein-1 (Reg3a) is overexpressed by pancreatic ACINAR CELLS in patients with CHRONIC PANCREATITIS. It is also highly expressed by pancreatic, bladder, and gastrointestinal cancer cells and may serve as a diagnostic biomarker.
Entry Term(s)
Pancreatitis-Associated Protein
Pancreatitis-Associated Protein-1
Regenerating Islet-Derived Protein
Regenerating Islet-Derived Protein 3
Regenerating Islet-Derived Proteins
Public MeSH Note
2018; PANCREATITIS-ASSOCIATED PROTEINS was indexed under PROTEINS 1992-1995, ACUTE-PHASE PROTEINS 1996-2001, CALCIUM-BINDING PROTEINS 2002 and LECTINS, C-TYPE 2003-2017
History Note
2018 (1992)
Date Established
2018/01/01
Date of Entry
2017/07/11
Revision Date
2021/05/10
Pancreatitis-Associated Proteins Preferred
Pancreatitis-Associated Protein-1 Narrower
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