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Receptors, N-Methyl-D-Aspartate MeSH Descriptor Data 2026
A class of ionotropic glutamate receptors characterized by affinity for N-methyl-D-aspartate. NMDA receptors have an allosteric binding site for glycine which must be occupied for the channel to open efficiently and a site within the channel itself to which magnesium ions bind in a voltage-dependent manner. The positive voltage dependence of channel conductance and the high permeability of the conducting channel to calcium ions (as well as to monovalent cations) are important in excitotoxicity and neuronal plasticity.
Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate-Associated Protein 1
N-Methyl D-Aspartate Receptor Subtype 2A
N-Methyl-D-Aspartate Receptor
N-Methyl-D-Aspartate Receptors
N-Methylaspartate Receptors
NMDA Receptor
NMDA Receptor 2A
NMDA Receptor A1
NMDA Receptor-Ionophore Complex
NMDA Receptors
NMDAR1
NMDAR2A Protein
NMDARA1 Protein
Receptor 2A, NMDA
Receptor A1, NMDA
Receptors, N-Methylaspartate
Receptors, NMDA
Registry Numbers
0
VH92ICR8HX
Related Numbers
VH92ICR8HX
Previous Indexing
Receptors, Cell Surface (1973-1984)
Receptors, Neurotransmitter (1985-1990)
Public MeSH Note
93; was RECEPTOR, N-METHYL-D-ASPARTATE 1991-92; N-METHYL-D-ASPARTATE RECEPTORS was N-METHYL-D-ASPARTATE RECEPTOR see RECEPTOR, N-METHYL-D-ASPARTATE 1991-92
Online Note
use RECEPTORS, N-METHYL-D-ASPARTATE to search RECEPTOR, N-METHYL-D-ASPARTATE & N-METHYL-D-ASPARTATE RECEPTOR 1991-92
History Note
93; was RECEPTOR, N-METHYL-D-ASPARTATE 1991-92; N-METHYL-D-ASPARTATE RECEPTORS was N-METHYL-D-ASPARTATE RECEPTOR see RECEPTOR, N-METHYL-D-ASPARTATE 1991-92
A class of ionotropic glutamate receptors characterized by affinity for N-methyl-D-aspartate. NMDA receptors have an allosteric binding site for glycine which must be occupied for the channel to open efficiently and a site within the channel itself to which magnesium ions bind in a voltage-dependent manner. The positive voltage dependence of channel conductance and the high permeability of the conducting channel to calcium ions (as well as to monovalent cations) are important in excitotoxicity and neuronal plasticity.