NLM Logo

Calponins MeSH Descriptor Data 2025


MeSH Heading
Calponins
Tree Number(s)
D05.750.078.730.266
D12.776.157.125.123
D12.776.210.500.187
D12.776.220.525.268
Unique ID
D000096985
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000096985
Scope Note
A family of actin binding proteins mostly in smooth muscle. Calponins include most abundant alpha-calponin (h1 or basic); beta-calponin; neutral calponin (h2 calponin); acidic calponin, SM22, and transgelin. Calponin family members have N-terminal single Calponin Homology (CH) domain and multiple C-terminus 23-amino acids long calponin-like repeats called CLICK-23. Calponins participate in modulation of smooth muscle contraction by binding to ACTINS (F- and G-Actins), CALMODULIN and TROPOMYSIN.
Entry Term(s)
Calponin
Calponin Family Proteins
Registry Numbers
0
Previous Indexing
Microfilament Proteins (1990-2023)
Public MeSH Note
2024
History Note
2024
Date Established
2024/01/01
Date of Entry
2023/07/26
Revision Date
2023/06/07
Calponins Preferred
page delivered in 0.135s