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Tensins MeSH Descriptor Data 2023


MeSH Heading
Tensins
Tree Number(s)
D05.750.078.730.719
D12.776.220.525.719
Unique ID
D000070876
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000070876
Scope Note
A family of multidomain microfilament proteins that bind ACTIN FILAMENTS and INTEGRINS at FOCAL ADHESIONS. They generally consist of an N-terminal domain with homology to PHOSPHOTYROSINE PHOSPHATASE, a C2 DOMAIN; unique central regions rich in PROLINE; ALANINE; GLYCINE; and SERINE; an SH2 DOMAIN; and a C-terminal phosphotyrosine-binding region. They are involved in CELL MIGRATION; CELL ADHESION; SIGNAL TRANSDUCTION; and reorganization of the CYTOSKELETON.
Entry Term(s)
Tensin
Registry Number
0
Public MeSH Note
2017; TENSINS was indexed under MICROFILAMENT PROTEINS (1992-2016)
History Note
2017 (1992)
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2016/02/26
Tensins Preferred
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