MeSH Browser

MeSH Heading: Actin Depolymerizing Factors
Tree Number(s): D05.750.078.730.212; D12.776.220.525.212
Unique ID: D051339
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051339
Scope Note: A family of low MOLECULAR WEIGHT actin-binding proteins found throughout eukaryotes. They remodel the actin CYTOSKELETON by severing ACTIN FILAMENTS and increasing the rate of monomer dissociation.
Entry Term(s): ADF Proteins (Actin Depolymerizing Factors); Actin Depolymerizing Protein; Actin Depolymerizing Proteins; Cofilin; Cofilin Proteins; Cofilins
Registry Numbers: 0
Public MeSH Note: 2006; ACTIN DEPOLYMERIZING FACTORS was indexed under MICROFILAMENT PROTEINS 1988-2005, & under MUSCLE PROTEINS & PROTEINS 1981-1987
History Note: 2006(1981)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0128858
Registry Numbers: 0
Scope Note: A family of low MOLECULAR WEIGHT actin-binding proteins found throughout eukaryotes. They remodel the actin CYTOSKELETON by severing ACTIN FILAMENTS and increasing the rate of monomer dissociation.
Terms: Actin Depolymerizing Factors Preferred Term
Term UI T629453
Date02/02/2005
LexicalTag NON
ThesaurusID NLM (2006); Actin Depolymerizing Protein
Term UI T000999764
Date11/29/2019
LexicalTag NON
ThesaurusID NLM (2021); Cofilin
Term UI T000999763
Date11/29/2019
LexicalTag NON
ThesaurusID NLM (2021); ADF Proteins (Actin Depolymerizing Factors)
Term UI T629454
Date02/02/2005
LexicalTag ACX
ThesaurusID NLM (2006); Cofilin Proteins
Term UI T629449
Date02/02/2005
LexicalTag NON
ThesaurusID NLM (2006); Cofilins
Term UI T629411
Date02/02/2005
LexicalTag NON
ThesaurusID NLM (2006); Actin Depolymerizing Proteins
Term UI T121224
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006)

Actin Depolymerizing Factors MeSH Descriptor Data 2025