MeSH Browser

MeSH Heading: Wiskott-Aldrich Syndrome Protein Family
Tree Number(s): D05.750.078.730.912; D12.776.220.525.912
Unique ID: D051300
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051300
Annotation: WISKOTT-ALDRICH SYNDROME PROTEIN and WISKOTT-ALDRICH SYNDROME PROTEIN, NEURONAL are also available
Scope Note: A family of microfilament proteins whose name derives from the fact that mutations in members of this protein family have been associated with WISKOTT-ALDRICH SYNDROME. They are involved in ACTIN polymerization and contain a polyproline-rich region that binds to PROFILIN, and a verprolin homology domain that binds G-ACTIN.
Entry Term(s): WAS Protein Family; WAS Protein Family, Member 1; WAS Protein Family, Member 2; WAS Protein Family, Member 3; WASF1 Protein; WASF2 Protein; WASF3 Protein; WASP Protein Family; WASP-Family Verprolin Homologous Proteins; WAVE Proteins; WAVE1 Protein; WAVE2 Protein; WAVE3 Protein; Wiskott-Aldrich Syndrome Protein Family, Member 1; Wiskott-Aldrich Syndrome Protein Family, Member 2; Wiskott-Aldrich Syndrome Protein Family, Member 3
Registry Number: 0
Public MeSH Note: 2006; WAVE PROTEINS was indexed under MICROFILAMENT PROTEINS 1999-2005
History Note: 2006(1999)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2013/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0480078
Registry Number: 0
Scope Note: A family of microfilament proteins whose name derives from the fact that mutations in members of this protein family have been associated with WISKOTT-ALDRICH SYNDROME. They are involved in ACTIN polymerization and contain a polyproline-rich region that binds to PROFILIN, and a verprolin homology domain that binds G-ACTIN.
Terms: Wiskott-Aldrich Syndrome Protein Family Preferred Term
Term UI T629245
Date01/31/2005
LexicalTag EPO
ThesaurusID NLM (2006); WASP Protein Family
Term UI T629246
Date01/31/2005
LexicalTag ACX
ThesaurusID NLM (2006); WAS Protein Family
Term UI T629327
Date02/01/2005
LexicalTag ACX
ThesaurusID NLM (2006)

Concept UI: M0480130
Registry Number: 0
Terms: Wiskott-Aldrich Syndrome Protein Family, Member 3 Preferred Term
Term UI T632978
Date03/10/2005
LexicalTag EPO
ThesaurusID NLM (2006); WASF3 Protein
Term UI T629338
Date02/01/2005
LexicalTag ACX
ThesaurusID NLM (2006); WAVE3 Protein
Term UI T629335
Date02/01/2005
LexicalTag ACX
ThesaurusID NLM (2006); WAS Protein Family, Member 3
Term UI T629337
Date02/01/2005
LexicalTag ACX
ThesaurusID NLM (2006)

Concept UI: M0480129
Registry Number: 0
Terms: Wiskott-Aldrich Syndrome Protein Family, Member 2 Preferred Term
Term UI T632977
Date03/10/2005
LexicalTag EPO
ThesaurusID NLM (2006); WASF2 Protein
Term UI T629334
Date02/01/2005
LexicalTag ACX
ThesaurusID NLM (2006); WAVE2 Protein
Term UI T629331
Date02/01/2005
LexicalTag ACX
ThesaurusID NLM (2006); WAS Protein Family, Member 2
Term UI T629333
Date02/01/2005
LexicalTag ACX
ThesaurusID NLM (2006)

Concept UI: M0301786
Registry Number: 0
Terms: Wiskott-Aldrich Syndrome Protein Family, Member 1 Preferred Term
Term UI T632976
Date03/10/2005
LexicalTag EPO
ThesaurusID NLM (2006); WASF1 Protein
Term UI T629231
Date01/31/2005
LexicalTag ACX
ThesaurusID NLM (2006); WAVE1 Protein
Term UI T372618
LexicalTag ACX
ThesaurusID NLM (2006); WAS Protein Family, Member 1
Term UI T424969
Date09/25/2000
LexicalTag ACX
ThesaurusID NLM (2006)

Wiskott-Aldrich Syndrome Protein Family MeSH Descriptor Data 2023