NLM Logo

Ryanodine Receptor Calcium Release Channel MeSH Descriptor Data 2025


MeSH Heading
Ryanodine Receptor Calcium Release Channel
Tree Number(s)
D12.776.157.530.400.150.800
D12.776.210.500.800
D12.776.543.550.450.150.800
D12.776.543.585.400.150.800
Unique ID
D019837
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D019837
Scope Note
A tetrameric calcium release channel in the SARCOPLASMIC RETICULUM membrane of SMOOTH MUSCLE CELLS, acting oppositely to SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES. It is important in skeletal and cardiac excitation-contraction coupling and studied by using RYANODINE. Abnormalities are implicated in CARDIAC ARRHYTHMIAS and MUSCULAR DISEASES.
Entry Version
RYANODINE RECEPT CALCIUM RELEASE CHANNEL
Entry Term(s)
Ca Release Channel-Ryanodine Receptor
Calcium-Ryanodine Receptor Complex
Receptor, Ryanodine
RyR1
RyR2
RyR3
Ryanodine Receptor
Ryanodine Receptor 1
Ryanodine Receptor 2
Ryanodine Receptor 3
Ryanodine Receptors
Previous Indexing
Calcium Channels (1988-1997)
Muscle Proteins (1993-1997)
Receptors, Cholinergic (1985-1992)
Public MeSH Note
98; CALCIUM-RYANODINE RECEPTOR COMPLEX (now RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL) was indexed under CALCIUM CHANNELS 1988-97, MUSCLE PROTEINS 1993-97, & RECEPTORS, CHOLINERGIC 1985-92
History Note
98; use RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL (NM) 1985-97
Entry Combination
agonists:Calcium Channel Agonists
antagonists & inhibitors:Calcium Channel Blockers
Date Established
1998/01/01
Date of Entry
1997/06/20
Revision Date
2016/07/01
Ryanodine Receptor Calcium Release Channel Preferred
Ryanodine Receptors Broader
Ryanodine Receptor 2 Narrower
Ryanodine Receptor 3 Narrower
Ryanodine Receptor 1 Narrower
page delivered in 0.155s