MeSH Browser

MeSH Heading: Calcium Channel Agonists
Tree Number(s): D27.505.519.562.124; D27.505.696.260.250; D27.505.954.411.793.205
Unique ID: D002120
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D002120
Scope Note: Agents that increase calcium influx into calcium channels of excitable tissues. This causes vasoconstriction in VASCULAR SMOOTH MUSCLE and/or CARDIAC MUSCLE cells as well as stimulation of insulin release from pancreatic islets. Therefore, tissue-selective calcium agonists have the potential to combat cardiac failure and endocrinological disorders. They have been used primarily in experimental studies in cell and tissue culture.
Entry Version: CALCIUM CHANNEL AG
Entry Term(s): Calcium Channel Activators; Calcium Channel Agonist; Calcium Channel Agonists, Exogenous; Exogenous Calcium Channel Agonists
Previous Indexing: Calcium/metab (1966-1987); Ion Channels (1979-1987)
Public MeSH Note: 88
History Note: 88
Entry Combination: antagonists & inhibitors:Calcium Channel Blockers
Date Established: 1988/01/01
Date of Entry: 1987/03/23
Revision Date: 2018/05/22

Entry Combination: antagonists & inhibitors:Calcium Channel Blockers
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0003163
Scope Note: Agents that increase calcium influx into calcium channels of excitable tissues. This causes vasoconstriction in VASCULAR SMOOTH MUSCLE and/or CARDIAC MUSCLE cells as well as stimulation of insulin release from pancreatic islets. Therefore, tissue-selective calcium agonists have the potential to combat cardiac failure and endocrinological disorders. They have been used primarily in experimental studies in cell and tissue culture.
Terms: Calcium Channel Agonists Preferred Term
Term UI T006038
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1988); Calcium Channel Activators
Term UI T006036
Date03/23/1987
LexicalTag NON
ThesaurusID UNK (19XX); Calcium Channel Agonist
Term UI T006037
Date04/20/1994
LexicalTag NON
ThesaurusID NLM (1995)

Calcium Channel Agonists MeSH Descriptor Data 2025