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Calcium Channels, L-Type MeSH Descriptor Data 2025


MeSH Heading
Calcium Channels, L-Type
Tree Number(s)
D12.776.157.530.400.150.400
D12.776.543.550.450.150.400
D12.776.543.585.400.150.400
Unique ID
D020746
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D020746
Scope Note
Long-lasting voltage-gated CALCIUM CHANNELS found in both excitable and non-excitable tissue. They are responsible for normal myocardial and vascular smooth muscle contractility. Five subunits (alpha-1, alpha-2, beta, gamma, and delta) make up the L-type channel. The alpha-1 subunit is the binding site for calcium-based antagonists. Dihydropyridine-based calcium antagonists are used as markers for these binding sites.
Entry Version
VDCC L
Entry Term(s)
Dihydropyridine Receptor
Dihydropyridine Receptors
L-Type Calcium Channel
L-Type Calcium Channels
L-Type VDCC
L-Type VDCC alpha-1 Subunit
L-Type VDCC alpha-2 Subunit
L-Type VDCC beta Subunit
L-Type VDCC delta Subunit
L-Type VDCC gamma Subunit
L-Type Voltage-Dependent Calcium Channel
L-Type Voltage-Dependent Calcium Channels
Long-Lasting Calcium Channel
Long-Lasting Calcium Channels
Receptors, Dihydropyridine
Previous Indexing
Calcium Channels (1993-1999)
Muscle Proteins (1993-1999)
Public MeSH Note
2000; DIHYDROPYRIDINE RECEPTOR (now L-TYPE CALCIUM CHANNELS) was indexed under CALCIUM CHANNELS & MUSCLE PROTEINS 1993-1999
History Note
2000; use L-TYPE CALCIUM CHANNELS (NM) 1993-1999
Date Established
2000/01/01
Date of Entry
1999/11/04
Revision Date
2021/06/30
Calcium Channels, L-Type Preferred
Receptors, Dihydropyridine Narrower
L-Type VDCC beta Subunit Narrower
L-Type VDCC delta Subunit Narrower
L-Type VDCC gamma Subunit Narrower
L-Type VDCC alpha-2 Subunit Narrower
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