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NAV1.4 Voltage-Gated Sodium Channel MeSH Descriptor Data 2023


MeSH Heading
NAV1.4 Voltage-Gated Sodium Channel
Tree Number(s)
D12.776.157.530.400.875.750.400
D12.776.210.500.675
D12.776.543.550.450.875.750.400
D12.776.543.585.400.875.750.400
Unique ID
D062553
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D062553
Scope Note
A voltage-gated sodium channel subtype that mediates the sodium ion PERMEABILITY of SKELETAL MYOCYTES. Defects in the SCN4A gene, which codes for the alpha subunit of this sodium channel, are associated with several MYOTONIC DISORDERS.
Entry Term(s)
NAV1.4 alpha Subunit
SCN4A Sodium Channel alpha Subunit
Sodium Channel, Voltage-Gated, Type IV, alpha 1 Subunit
Type 4 Voltage-Gated Sodium Channel
Voltage-Gated Sodium Channel Type 4
Voltage-Gated Sodium Channel Type 4 Subunit alpha
Registry Number
0
Previous Indexing
Sodium Channels (1989-2012)
See Also
Hypokalemic Periodic Paralysis
Paralysis, Hyperkalemic Periodic
Public MeSH Note
2013
History Note
2013
Entry Combination
agonists:Voltage-Gated Sodium Channel Agonists
antagonists & inhibitors:Voltage-Gated Sodium Channel Blockers
Date Established
2013/01/01
Date of Entry
2012/07/03
Revision Date
2016/07/01
NAV1.4 Voltage-Gated Sodium Channel Preferred
Voltage-Gated Sodium Channel Type 4 Subunit alpha Narrower
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