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NAV1.1 Voltage-Gated Sodium Channel MeSH Descriptor Data 2023


MeSH Heading
NAV1.1 Voltage-Gated Sodium Channel
Tree Number(s)
D12.776.157.530.400.875.750.100
D12.776.543.550.450.875.750.100
D12.776.543.585.400.875.750.100
D12.776.631.960.100
Unique ID
D062550
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D062550
Scope Note
A voltage-gated sodium channel subtype that is predominantly expressed in the CENTRAL NERVOUS SYSTEM. Defects in the SCN1A gene which codes for the alpha subunit of this sodium channel are associated with DRAVET SYNDROME, generalized epilepsy with febrile seizures plus, type 2 (GEFS+2), and familial hemiplegic migraine type 3.
Entry Term(s)
NAV1.1 alpha Subunit
SCN1A Sodium Channel alpha Subunit
Sodium Channel, Voltage-Gated, Type I, alpha Protein
Type 1 Voltage-Gated Sodium Channel
Voltage-Gated Sodium Channel Type 1
Voltage-Gated Sodium Channel Type 1 Subunit alpha
Voltage-Gated Sodium Channel Type 1 alpha Subunit
Registry Number
0
Previous Indexing
Sodium Channels (1989-2012)
See Also
Epilepsies, Myoclonic
Public MeSH Note
2013; SODIUM CHANNEL, VOLTAGE-GATED, TYPE I, ALPHA PROTEIN was indexed under SODIUM CHANNELS 2000-2012
History Note
2013
Entry Combination
agonists:Voltage-Gated Sodium Channel Agonists
antagonists & inhibitors:Voltage-Gated Sodium Channel Blockers
Date Established
2013/01/01
Date of Entry
2012/07/03
Revision Date
2016/07/01
NAV1.1 Voltage-Gated Sodium Channel Preferred
Voltage-Gated Sodium Channel Type 1 Subunit alpha Narrower
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